Monitoring of UV filters uptake/release from polyether-ureasil hybrid materials

• Processo: 11/12087-8
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado
• Data de Início da vigência: 01 de setembro de 2011
• Data de Término da vigência: 31 de outubro de 2013
• Área de conhecimento: Engenharias - Engenharia de Materiais e Metalúrgica - Materiais Não-metálicos
• Pesquisador responsável: Sandra Helena Pulcinelli
• Beneficiário: Laurianne Truffault
• Instituição Sede: Instituto de Química (IQ). Universidade Estadual Paulista (UNESP). Campus de Araraquara. Araraquara , SP, Brasil
• Vinculado ao auxílio: 07/53073-4 - Cerâmicas mesoporosas e hibridos orgânico-inorgânicos multifuncionais preparados pelo processo sol-gel, AP.TEM
• Palavra(s)-Chave do Pesquisador: siloxane-polyether hybrids | structural features | UV filters release | nanomaterials/ hybrid materials

Resumo

The ability of assembling inorganic, organic, and even bioactive components in a single material unfolds an exciting direction in the development of novel multifunctional hybrid materials. Recently, we have observed that flexible, transparent and insoluble urea-cross-linked polyether/siloxane hybrids presenting a tunable drug delivery pattern could be prepared using the sol-gel method from PEO (poly(ethylene oxide)) and PPO (poly(propylene oxide)) of different polyether chain lengths functionalized at both chain ends with triethoxysilane. The ability to adapt the process established for drugs (CisPt and SDCF) to UV filters used as active ingredients in sunscreens would open new possibilities in the photoprotection field. Recently, the trend in photoprotection is the increased use of inorganic UV filters, which are usually made of nanostructured metallic oxide particles, for both photoprotection efficiency and aesthetic purposes. Goals:* to establish new protocols of hybrid materials preparation/characterization from nanoparticle incorporation and/or Raman, UV-Vis and NMR spectroscopies;* to "adapt" the process established for the drug delivery to inorganic nanoparticulated UV filters by incorporating pure or doped inorganic oxide (cerium, iron, tin, titanium or zinc) in the hybrid matrix;* to establish structure-properties correlations taking account for both the matrix and the NP structure/size and the release transport phenomenon.

Publicações científicas

(Referências obtidas automaticamente do Web of Science e do SciELO, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores)

TRUFFAULT, L.; MAGNANI, M.; HAMMER, P.; SANTILLI, C. V.; PULCINELLI, S. H.. Structural and optical features of ureasiloxane-polyethylene oxide hybrids containing CeO2 nanoparticles. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, v. 471, p. 73-80, APR 20 2015. (11/12087-8)