| Texto completo | |
| Autor(es): Mostrar menos - |
Garcia, Cilmara P.
[1, 2]
;
Rosa, Juliana F.
[1, 2]
;
Cursino, Maria A.
[1, 2]
;
Lobo, Renata D.
[3]
;
Mollaco, Carla H.
[3]
;
Gobara, Satiko
[3]
;
Malieno, Paula B.
[1, 2]
;
Raymundo, Gabriela F.
[1, 2]
;
Soares, Robson E.
[1, 2]
;
Keil, Kleiste G.
[1, 2]
;
Toma, Edi
[4]
;
Salomao, Matias C.
[1, 2]
;
Helena Matte, M.
[5]
;
Krebs, Vera L.
[4]
;
Augusta Gibelli, M.
[4]
;
Kondo, Mario M.
[6]
;
Zugaib, Marcelo
[6]
;
Costa, Silvia F.
[7, 1, 2]
;
Levin, Anna S.
[7, 1, 2, 3]
Número total de Autores: 19
|
| Afiliação do(s) autor(es): | [1] Univ Sao Paulo, Hosp Clin, Dept Infect Dis, Sao Paulo - Brazil
[2] Univ Sao Paulo, Hosp Clin, LIM 54, Sao Paulo - Brazil
[3] Univ Sao Paulo, Hosp Clin, Dept Infect Control, Sao Paulo - Brazil
[4] Univ Sao Paulo, Dept Pediat, Sao Paulo - Brazil
[5] Univ Sao Paulo, Fac Publ Hlth, Sao Paulo - Brazil
[6] Univ Sao Paulo, Dept Obstet, Sao Paulo - Brazil
[7] Univ Sao Paulo, Inst Med Trop Sao Paulo, Sao Paulo - Brazil
Número total de Afiliações: 7
|
| Tipo de documento: | Artigo Científico |
| Fonte: | PEDIATRIC INFECTIOUS DISEASE JOURNAL; v. 33, n. 10, p. E252-E259, OCT 2014. |
| Citações Web of Science: | 3 |
| Resumo | |
Background: In the last decade, non-multiresistant methicillin-resistant Staphylococcus aureus (NM-MRSA) has been described as an important agent in bloodstream infections in our hospital. Methods: This prospective cohort study, conducted from February 2009 through January 2010 in the neonatal unit, evaluated 403 newborns (NB), their 382 mothers and 148 health care workers (HCW). Results: Approximately 217 NB (54%), 187 mothers (48%) and 87 HCW (59%) were colonized by S. aureus (SA). MRSA colonization was greater among NB (15%) than mothers (4.7%) and HCW (3.4%). Although mother-to-NB transmission occurred, in most cases mothers were not responsible for NB colonization. There were 2 predominant PFGE patterns among the NB and some mothers and HCW became colonized by them. Factors significantly associated with MRSA carriage by NB were lower level of maternal schooling (risk factor: odds ratio: 2.99; 95% confidence interval: 1.10-8.07) and maternal rhinosinusitis (protective factor: odds ratio: 0.33; 95% confidence interval: 0.12-0.88). Among NB who remained hospitalized for more than 72 hours, breast feeding was protective (odds ratio: 0.22; 95% confidence interval: 0.05-0.98). All the isolates were NM-MRSA, carried few virulence factors and SCCmec types IVa and type IVd predominated. Conclusions: Although there were no cases of infection, nosocomial transmission of MRSA clearly occurred in the neonatal unit, and this highlights the need for infection control practices such as hand hygiene to prevent cross-dissemination. Other healthcare practices, which are very basic but also ample in scope, may play a role, such as general education of women and breast feeding. (AU) | |
| Processo FAPESP: | 09/07746-2 - Estudo da prevalência de S. aureus resistente à oxacilina em recém-nascidos e suas mães |
| Beneficiário: | Matias Chiarastelli Salomão |
| Modalidade de apoio: | Bolsas no Brasil - Iniciação Científica |
| Processo FAPESP: | 09/08206-1 - Fatores associados à aquisição de Staphylococcus aureus resistentes à oxacilina (MRSA) em recém-nascidos de parto hospitalar |
| Beneficiário: | Anna Sara Shafferman Levin |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |