| Texto completo | |
| Autor(es): |
Filogonio, Renato
[1]
;
Taylor, Edwin W.
[1, 2]
;
Carreira, Laura B. T.
[1, 3]
;
Leite, Gabrielle S. P. C.
[4]
;
Abe, Augusto S.
[1, 3]
;
Leite, Cleo A. C.
[5]
Número total de Autores: 6
|
| Afiliação do(s) autor(es): | [1] State Univ Sao Paulo, Dept Zool, BR-13506900 Rio Claro, SP - Brazil
[2] Univ Birmingham, Sch Biosci, Birmingham B15 2TT, W Midlands - England
[3] State Univ Sao Paulo, Dept Aquaculture, BR-14884900 Jaboticabal, SP - Brazil
[4] ADInstruments Brazil, BR-04109080 Sao Paulo - Brazil
[5] Univ Fed Sao Carlos, Dept Physiol Sci, BR-13565905 Sao Carlos, SP - Brazil
Número total de Afiliações: 5
|
| Tipo de documento: | Artigo Científico |
| Fonte: | South American Journal of Herpetology; v. 9, n. 3, p. 171-176, DEC 2014. |
| Citações Web of Science: | 3 |
| Resumo | |
Estimating total systemic blood flow based on measurements from a single aortic arch is common practice in cardiovascular studies on reptiles to avoid heavy instrumentation and consequent stress responses. This practice requires the validation of a specific correction factor that expresses the relationship between the measured blood flow and the blood flow to be estimated. Misleading estimations may occur when correction factors are used in different conditions from those they were originally measured. Despite recognized as a problem, such misleading estimations are common in physiology. In the present study, we derived values for correction factors to estimate systemic blood flow in the South American rattlesnake, Crotalus durissus, following recovery from anesthesia, using serial measurements of blood flow in the three main systemic arteries, left or distal right aortic arches and the carotid artery. Blood flow recorded in the left aortic arch provided the most reliable and less variable correction factors. Different from previously published, blood flow distribution in the systemic circulation varied with temperature. We suggest the use of the specific correction factors present in this paper for different experimental protocols and temperatures. Furthermore, we can affirm that unilateral left vagotomy, which effectively ablated control of right-left shunts, does not affect systemic blood flow distribution, so the same correction factors can be used. (AU) | |
| Processo FAPESP: | 08/57712-4 - Instituto Nacional de Pesquisas em Fisiologia Comparada |
| Beneficiário: | Augusto Shinya Abe |
| Modalidade de apoio: | Auxílio à Pesquisa - Temático |
| Processo FAPESP: | 12/06938-8 - Desenvolvimento do controle neural no sistema cardiovascular de répteis |
| Beneficiário: | Augusto Shinya Abe |
| Modalidade de apoio: | Auxílio à Pesquisa - Pesquisador Visitante - Internacional |