Short communication: Variable number of tandem repeat polymorphisms in DGAT1 gene of buffaloes (Bubalus bubalis) is associated with milk constituents

Autor(es)

Cardoso, D. F. ^[1] ; de Souza, G. F. P. ^[1] ; Aspilcueta-Borquis, R. R. ^[1] ; Neto, F. R. Araujo ^[2] ; de Camargo, G. M. F. ^[1] ; Hurtado-Lugo, N. A. ^[1] ; Scalez, D. C. B. ^[1] ; de Freitas, A. C. ^[1] ; Albuquerque, L. G. ^[1] ; Tonhati, H. ^[1]

Afiliação do(s) autor(es)

^[1] Univ Estadual Paulista UNESP, Fac Ciencias Agr & Vet, Dept Zootecnia, BR-14884900 Jaboticabal, SP - Brazil

^[2] Inst Fed Goiano, BR-75901970 Rio Verde, Go - Brazil

• Tipo de documento: Artigo Científico
• Fonte: JOURNAL OF DAIRY SCIENCE; v. 98, n. 5, p. 3492-3495, MAY 2015.
• Citações Web of Science: 5

Resumo

The diacylglycerol-O-transferase 1 gene is a positional and functional candidate for milk composition traits. The objective of this study was to evaluate the segregation of the variable number of tandem repeat polymorphisms in the regulatory region of diacylglycerol- O-transferase 1 gene in a water buffalo herd, and to assess the association of this mutation with milk production traits. For this purpose, 196 Murrah buffalo cows were genotyped by PCR. The association of the marker with total milk, fat, and protein yields at 305 d of lactation, milk fat and protein percentage, and somatic cell scores were evaluated by single-trait analyses using a generalized mixed model. Two segregating alleles were identified in the population. The allele with 2 repeats affected fat percentage favorably. The present results suggest that this polymorphism is an interesting marker to include in the genetic evaluation of buffaloes. (AU)

• Processo FAPESP: 11/22163-3 - Busca de polimorfismos causais em genes candidatos por análises genômicas e suas associações com a probabilidade de prenhez precoce em novilhas da raça Nelore
• Beneficiário: Humberto Tonhati
• Modalidade de apoio: Auxílio à Pesquisa - Regular