Serum DHEA-S increases in dogs naturally infected with Ehrlichia canis

Autor(es)

Rondelli, M. C. H. ^[1] ; Munhoz, T. D. ^[2] ; Catandi, P. B. ^[3] ; Freschi, C. R. ^[4] ; Palacios Junior, R. J. G. ^[5] ; Machado, R. Z. ^[4] ; Tinucci-Costa, M. ^[1]

Afiliação do(s) autor(es)

^[1] Univ Estadual Paulista, Dept Vet Clin & Surg, Fac Ciencias Agr & Vet, BR-14884900 Jaboticabal, SP - Brazil

^[2] Ctr Univ Barao de Maua, BR-14031580 Ribeirao Preto, SP - Brazil

^[3] Autonomous Vet, BR-15800190 Catanduva, SP - Brazil

^[4] Univ Estadual Paulista, Fac Ciancias Agr & Vet, Dept Vet Pathol, BR-14884900 Jaboticabal, SP - Brazil

^[5] Autonomous Vet, BR-04326080 Sao Paulo, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Research in Veterinary Science; v. 100, p. 18-20, JUN 2015.
• Citações Web of Science: 1

Resumo

Adrenocortical disturbances are expected in canine ehrlichiosis due to the immunological challenges caused by infection and consequent inflammation. Thus, this study aimed to evaluate the occurrence of adrenocortical hormonal alterations in dogs naturally infected with Ehrlichia canis (n=21) as positively confirmed by the presence of anti-E. cartis antibodies (Dot-ELISA) and nested PCR (nPCR). Serum dehydroepiandrosterone sulfate (DHEA-S) concentrations were assessed via ELISA before and one hour after ACTH stimulation. Another 10 healthy dogs were subjected to the same stimulation protocol and used as controls. The results revealed that baseline and post-ACTH DHEA-S concentrations were significantly greater in sick dogs, regardless of gender, and this finding illustrates the stress induced by naturally acquired ehrlichiosis in dogs. (C) 2015 Elsevier Ltd. All rights reserved. (AU)

• Processo FAPESP: 10/02676-3 - Avaliação hormonal adrenocortical em cães com infecção natural por Ehrlichia canis
• Beneficiário: Mariana Cristina Hoeppner Rondelli
• Modalidade de apoio: Bolsas no Brasil - Mestrado
• Processo FAPESP: 10/11630-7 - Avaliação hormonal adrenocortical em cães com infecção natural por Ehrlichia canis
• Beneficiário: Mirela Tinucci Costa
• Modalidade de apoio: Auxílio à Pesquisa - Regular