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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Serum DHEA-S increases in dogs naturally infected with Ehrlichia canis

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Author(s):
Rondelli, M. C. H. [1] ; Munhoz, T. D. [2] ; Catandi, P. B. [3] ; Freschi, C. R. [4] ; Palacios Junior, R. J. G. [5] ; Machado, R. Z. [4] ; Tinucci-Costa, M. [1]
Total Authors: 7
Affiliation:
[1] Univ Estadual Paulista, Dept Vet Clin & Surg, Fac Ciencias Agr & Vet, BR-14884900 Jaboticabal, SP - Brazil
[2] Ctr Univ Barao de Maua, BR-14031580 Ribeirao Preto, SP - Brazil
[3] Autonomous Vet, BR-15800190 Catanduva, SP - Brazil
[4] Univ Estadual Paulista, Fac Ciancias Agr & Vet, Dept Vet Pathol, BR-14884900 Jaboticabal, SP - Brazil
[5] Autonomous Vet, BR-04326080 Sao Paulo, SP - Brazil
Total Affiliations: 5
Document type: Journal article
Source: Research in Veterinary Science; v. 100, p. 18-20, JUN 2015.
Web of Science Citations: 1
Abstract

Adrenocortical disturbances are expected in canine ehrlichiosis due to the immunological challenges caused by infection and consequent inflammation. Thus, this study aimed to evaluate the occurrence of adrenocortical hormonal alterations in dogs naturally infected with Ehrlichia canis (n=21) as positively confirmed by the presence of anti-E. cartis antibodies (Dot-ELISA) and nested PCR (nPCR). Serum dehydroepiandrosterone sulfate (DHEA-S) concentrations were assessed via ELISA before and one hour after ACTH stimulation. Another 10 healthy dogs were subjected to the same stimulation protocol and used as controls. The results revealed that baseline and post-ACTH DHEA-S concentrations were significantly greater in sick dogs, regardless of gender, and this finding illustrates the stress induced by naturally acquired ehrlichiosis in dogs. (C) 2015 Elsevier Ltd. All rights reserved. (AU)

FAPESP's process: 10/02676-3 - Adrenocortical hormonal evaluation in dogs with natural infection by Ehrlichia canis
Grantee:Mariana Cristina Hoeppner Rondelli
Support Opportunities: Scholarships in Brazil - Master
FAPESP's process: 10/11630-7 - Adrenocortical hormonal evaluation in dogs with natural infection by Ehrlichia canis
Grantee:Mirela Tinucci Costa
Support Opportunities: Regular Research Grants