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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Accuracy of dose planning for prostate radiotherapy in the presence of metallic implants evaluated by electron spin resonance dosimetry

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Autor(es):
Alves, G. G. [1] ; Kinoshita, A. [2, 1] ; de Oliveira, H. F. [3] ; Guimaraes, F. S. [3] ; Amaral, L. L. [3] ; Baffa, O. [1]
Número total de Autores: 6
Afiliação do(s) autor(es):
[1] Univ Sao Paulo, Fac Filosofia Ciencias & Letras Ribeirao Preto, Dept Fis, Ribeirao Preto, SP - Brazil
[2] Univ Sagrado Coracao, Bauru, SP - Brazil
[3] Univ Sao Paulo, Fac Med Ribeirao Preto, Hosp Clin, Serv Radioterapia, Ribeirao Preto, SP - Brazil
Número total de Afiliações: 3
Tipo de documento: Artigo Científico
Fonte: Brazilian Journal of Medical and Biological Research; v. 48, n. 7, p. 644-649, JUN 2015.
Citações Web of Science: 3
Resumo

Radiotherapy is one of the main approaches to cure prostate cancer, and its success depends on the accuracy of dose planning. A complicating factor is the presence of a metallic prosthesis in the femur and pelvis, which is becoming more common in elderly populations. The goal of this work was to perform dose measurements to check the accuracy of radiotherapy treatment planning under these complicated conditions. To accomplish this, a scale phantom of an adult pelvic region was used with alanine dosimeters inserted in the prostate region. This phantom was irradiated according to the planned treatment under the following three conditions: with two metallic prostheses in the region of the femur head, with only one prosthesis, and without any prostheses. The combined relative standard uncertainty of dose measurement by electron spin resonance (ESR)/alanine was 5.05%, whereas the combined relative standard uncertainty of the applied dose was 3.35%, resulting in a combined relative standard uncertainty of the whole process of 6.06%. The ESR dosimetry indicated that there was no difference (P>0.05, ANOVA) in dosage between the planned dose and treatments. The results are in the range of the planned dose, within the combined relative uncertainty, demonstrating that the treatment-planning system compensates for the effects caused by the presence of femur and hip metal prostheses. (AU)

Processo FAPESP: 07/06720-4 - Avanços em dosimetria, datação arqueológica e caracterização de biomateriais por ressonância de spin eletrônico
Beneficiário:Oswaldo Baffa Filho
Modalidade de apoio: Auxílio à Pesquisa - Regular