| Texto completo | |
| Autor(es): |
Lemos Fochi, Mariana Machado
[1, 2]
;
Baring, Sabrina
[3]
;
Junqueira Franco Spegiorin, Ligia Cosentino
[3, 4, 5, 1]
;
Mos Vaz-Oliani, Denise Cristina
[3, 4, 5]
;
Galao, Eloisa Aparecida
[3, 4, 5]
;
Oliani, Antonio Helio
[4, 5]
;
de Mattos, Luiz Carlos
[1, 2]
;
Brandao de Mattos, Cinara Cassia
[1, 2]
Número total de Autores: 8
|
| Afiliação do(s) autor(es): | [1] Fac Med Sao Jose do Rio Preto FAMERP, FAMERP Toxoplasma Res Grp, Sao Jose Do Rio Preto, SP - Brazil
[2] Fac Med Sao Jose do Rio Preto FAMERP, Dept Mol Biol, Immunogenet Lab, Sao Jose Do Rio Preto, SP - Brazil
[3] Fundacao Fac Reg Med Sao Jose do Rio Preto HB FUN, Hosp Base, Obstet & Gynecol Serv, Sao Jose Do Rio Preto, SP - Brazil
[4] Fac Med Sao Jose do Rio Preto FAMERP, Dept Gynecol & Obstet, Sao Jose Do Rio Preto, SP - Brazil
[5] Hosp Crianca & Maternidade Sao Jose do Rio Preto, Sao Jose Do Rio Preto, SP - Brazil
Número total de Afiliações: 5
|
| Tipo de documento: | Artigo Científico |
| Fonte: | PLoS One; v. 10, n. 7 JUL 20 2015. |
| Citações Web of Science: | 4 |
| Resumo | |
Gestational Toxoplasma gondii infection is considered a major risk factor for miscarriage, prematurity and low birth weight in animals. However, studies focusing on this topic in humans are scarce. The objective of this study is to determine whether anti-Toxoplasma gondii maternal serum profiles correlate prematurity and low birth weight in humans. The study examined 213 pregnant women seen at the High-Risk Pregnancy Hospital de Base, Sao Jose do Rio Preto, Sao Paulo, Brazil. All serological profiles (IgM-/IgG+; IgM-/IgG-; IgM +/IgG+) were determined by ELISA commercial kits. Maternal age, gestational age and weight of the newborn at birth were collected and recorded in the Statement of Live Birth. Prematurity was defined as gestational age <37 weeks and low birth weight <= 2499 grams. The t-test was used to compare values (p < 0.05). The mean maternal age was 27.6 +/- 6.6 years. Overall, 56.3% (120/213) of the women studied were IgM-/IgG+, 36.2% (77/213) were IgM-/IgG-and 7.5% (16/213) were IgM+/IgG+. The average age of the women with serological profile IgM+/IgG+ (22.3 +/- 3.9 years) was different from women with the profile IgM-/IgG+ (27.9 +/- 6.7 years, p = 0.0011) and IgM-/IgG-(27.9 +/- 6.4 years, p = 0.0012). There was no statistically significant difference between the different serological profiles in relation to prematurity (p = 0.6742) and low birth weight (p = 0.7186). The results showed that prematurity and low birth weight did not correlate with anti-Toxoplasma gondii maternal serum profiles. (AU) | |
| Processo FAPESP: | 09/17540-2 - Sistemas histo-sanguíneos como fatores de risco para a toxoplasmose ocular |
| Beneficiário: | Luiz Carlos de Mattos |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |
| Processo FAPESP: | 13/03269-0 - 12th International Congress on Toxoplasmosis |
| Beneficiário: | Cinara de Cássia Brandão |
| Modalidade de apoio: | Auxílio à Pesquisa - Reunião - Exterior |