Properties of the tibialis anterior muscle after treatment with laser therapy and natural latex protein following sciatic nerve crush

Autor(es):Mostrar menos -

Muniz, Kenia Lemos ^[1] ; Dias, Fernando Jose ^{[2, 3]} ; Coutinho-Netto, Joaquim ^[2] ; Junqueira Calzzani, Ricardo Alexandre ^[1] ; Iyomasa, Mamie Mizusaki ^[1] ; De Sousa, Luiz Gustavo ^[1] ; Dos Santos, Thais Tedeschi ^[1] ; Teles, Vanessa De Oliveira ^[1] ; Watanabe, II-Sei ^[3] ; Sassoli Fazan, Valeria Paula ^[2] ; Mardegan Issa, Joao Paulo ^[1]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Fac Dent Ribeirao Preto, BR-14049 Ribeirao Preto - Brazil

^[2] Univ Sao Paulo, Fac Med Ribeirao Preto, BR-14049 Ribeirao Preto - Brazil

^[3] Univ Sao Paulo, Inst Biomed Sci, BR-14049 Ribeirao Preto - Brazil

• Tipo de documento: Artigo Científico
• Fonte: MUSCLE & NERVE; v. 52, n. 5, p. 869-875, NOV 2015.
• Citações Web of Science: 4

Resumo

Introduction: In this study we evaluated the characteristics of the tibialis anterior muscle after sciatic nerve crush and treatment with low-level laser therapy (LLLT) or the protein from natural latex (P1). Methods: We studied the following 6 groups of male Wistar rats: control (CG); exposed nerve (EG); injured nerve (IG); injured nerve with LLLT (LG); injured nerve with P1 (PG); and injured nerve with P1 and LLLT (LPG). Results: After 4 weeks, muscle morphology showed improvement in the treated groups; after 8 weeks, the treated groups resembled controls, especially the PG. Morphometry revealed muscle fiber atrophy after nerve injury, with time-dependent recovery. Histochemical analysis revealed increased intermediate fiber area. The PG was more similar to controls with NADH staining, whereas the LPG more closely resembled controls with SDH staining. Conclusion: Treatment using only P1 proved most efficient, revealing a negative interaction between P1 and LLLT. Muscle Nerve52: 869-875, 2015 (AU)

• Processo FAPESP: 11/01326-1 - Análise do músculo tibial anterior após a lesão por esmagamento do nervo isquiático e tratamento com laser de baixa intensidade associado à proteína purificada do látex natural (Hevea brasiliensis) em ratos Wistar
• Beneficiário: Kenia Lemos Muniz
• Modalidade de apoio: Bolsas no Brasil - Iniciação Científica