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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Properties of the tibialis anterior muscle after treatment with laser therapy and natural latex protein following sciatic nerve crush

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Author(s):
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Muniz, Kenia Lemos [1] ; Dias, Fernando Jose [2, 3] ; Coutinho-Netto, Joaquim [2] ; Junqueira Calzzani, Ricardo Alexandre [1] ; Iyomasa, Mamie Mizusaki [1] ; De Sousa, Luiz Gustavo [1] ; Dos Santos, Thais Tedeschi [1] ; Teles, Vanessa De Oliveira [1] ; Watanabe, II-Sei [3] ; Sassoli Fazan, Valeria Paula [2] ; Mardegan Issa, Joao Paulo [1]
Total Authors: 11
Affiliation:
[1] Univ Sao Paulo, Fac Dent Ribeirao Preto, BR-14049 Ribeirao Preto - Brazil
[2] Univ Sao Paulo, Fac Med Ribeirao Preto, BR-14049 Ribeirao Preto - Brazil
[3] Univ Sao Paulo, Inst Biomed Sci, BR-14049 Ribeirao Preto - Brazil
Total Affiliations: 3
Document type: Journal article
Source: MUSCLE & NERVE; v. 52, n. 5, p. 869-875, NOV 2015.
Web of Science Citations: 4
Abstract

Introduction: In this study we evaluated the characteristics of the tibialis anterior muscle after sciatic nerve crush and treatment with low-level laser therapy (LLLT) or the protein from natural latex (P1). Methods: We studied the following 6 groups of male Wistar rats: control (CG); exposed nerve (EG); injured nerve (IG); injured nerve with LLLT (LG); injured nerve with P1 (PG); and injured nerve with P1 and LLLT (LPG). Results: After 4 weeks, muscle morphology showed improvement in the treated groups; after 8 weeks, the treated groups resembled controls, especially the PG. Morphometry revealed muscle fiber atrophy after nerve injury, with time-dependent recovery. Histochemical analysis revealed increased intermediate fiber area. The PG was more similar to controls with NADH staining, whereas the LPG more closely resembled controls with SDH staining. Conclusion: Treatment using only P1 proved most efficient, revealing a negative interaction between P1 and LLLT. Muscle Nerve52: 869-875, 2015 (AU)

FAPESP's process: 11/01326-1 - Analysis of the anterior tibial muscle after lesion of the sciatic nerve by crash and treatment with low-intensity laser associated to purified protein from natural latex (Hevea brasiliensis) in Wistar rats
Grantee:Kenia Lemos Muniz
Support Opportunities: Scholarships in Brazil - Scientific Initiation