Protective effect of experimental mouthrinses containing NaF and TiF4 on dentin erosive loss in vitro

Autor(es)

Freire de Castilho, Aline Rogeria ^[1] ; Aranda Salomao, Priscila Maria ^[2] ; Rabelo Buzalaf, Marlia Afonso ^[2] ; Magalhaes, Ana Carolina ^[2]

Afiliação do(s) autor(es)

^[1] Univ Estadual Campinas, Fac Odontol Piracicaba, Dept Ciencias Fisiol, Campinas, SP - Brazil

^[2] Univ Sao Paulo, Fac Odontol Bauru, Dept Ciencias Biol, Sao Paulo, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Journal of Applied Oral Science; v. 23, n. 5, p. 486-490, SEP-OCT 2015.
• Citações Web of Science: 8

Resumo

Objective This in vitro study assessed the anti-erosive effect of experimental mouthrinses containing TiF4 and NaF on dentin erosive loss. Material and Methods Bovine dentin specimens were randomly allocated into the groups (n=15): 1) SnCl2/NaF/AmF (Erosion Protection®/GABA, pH 4.5, positive control); 2) experimental solution with 0.0815% TiF4 (pH 2.5); 3) 0.105% NaF (pH 4.5); 4) 0.042% NaF+0.049% TiF4 (pH 4.4); 5) 0.063% NaF+0.036% TiF4 (pH 4.5); 6) no treatment (negative control). Each specimen was cyclically demineralized (Sprite Zero, pH 2.6, 4x90 s/day) and exposed to artificial saliva between the erosive challenges for 7 days. The treatment with the fluoride solutions was done 2x60 s/day, immediately after the first and the last erosive challenges of the day. Dentin erosive loss was measured by profilometry (μm). The data were analyzed using Kruskal Wallis/Dunn tests (p<0.05). Results Mouthrinses containing TiF4 or Sn/F were able to show some protective effect against dentin erosive loss compared to negative control. The best anti-erosive effect was found for experimental solution containing 0.0815% TiF4 (100% reduction in dentin loss), followed by 0.042% NaF+0.049% TiF4 (58.3%), SnCl2/NaF/AmF (52%) and 0.063% NaF+0.036% TiF4 (40%). NaF solution (13.3%) did not significantly differ from control. Conclusion The daily application of experimental mouthrinse containing TiF4 and NaF has the ability to reduce dentin erosion, as well as Erosion Protection® and TiF4 alone. (AU)

• Processo FAPESP: 12/20698-0 - Efeito do TiF4 sobre hidroxiapatita e esmalte submetidos a processos cariogênicos e erosivos: estudos in vitro e in situ
• Beneficiário: Ana Carolina Magalhães
• Modalidade de apoio: Auxílio à Pesquisa - Regular