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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Protective effect of experimental mouthrinses containing NaF and TiF4 on dentin erosive loss in vitro

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Author(s):
Freire de Castilho, Aline Rogeria [1] ; Aranda Salomao, Priscila Maria [2] ; Rabelo Buzalaf, Marlia Afonso [2] ; Magalhaes, Ana Carolina [2]
Total Authors: 4
Affiliation:
[1] Univ Estadual Campinas, Fac Odontol Piracicaba, Dept Ciencias Fisiol, Campinas, SP - Brazil
[2] Univ Sao Paulo, Fac Odontol Bauru, Dept Ciencias Biol, Sao Paulo, SP - Brazil
Total Affiliations: 2
Document type: Journal article
Source: Journal of Applied Oral Science; v. 23, n. 5, p. 486-490, SEP-OCT 2015.
Web of Science Citations: 8
Abstract

Objective This in vitro study assessed the anti-erosive effect of experimental mouthrinses containing TiF4 and NaF on dentin erosive loss. Material and Methods Bovine dentin specimens were randomly allocated into the groups (n=15): 1) SnCl2/NaF/AmF (Erosion Protection®/GABA, pH 4.5, positive control); 2) experimental solution with 0.0815% TiF4 (pH 2.5); 3) 0.105% NaF (pH 4.5); 4) 0.042% NaF+0.049% TiF4 (pH 4.4); 5) 0.063% NaF+0.036% TiF4 (pH 4.5); 6) no treatment (negative control). Each specimen was cyclically demineralized (Sprite Zero, pH 2.6, 4x90 s/day) and exposed to artificial saliva between the erosive challenges for 7 days. The treatment with the fluoride solutions was done 2x60 s/day, immediately after the first and the last erosive challenges of the day. Dentin erosive loss was measured by profilometry (μm). The data were analyzed using Kruskal Wallis/Dunn tests (p<0.05). Results Mouthrinses containing TiF4 or Sn/F were able to show some protective effect against dentin erosive loss compared to negative control. The best anti-erosive effect was found for experimental solution containing 0.0815% TiF4 (100% reduction in dentin loss), followed by 0.042% NaF+0.049% TiF4 (58.3%), SnCl2/NaF/AmF (52%) and 0.063% NaF+0.036% TiF4 (40%). NaF solution (13.3%) did not significantly differ from control. Conclusion The daily application of experimental mouthrinse containing TiF4 and NaF has the ability to reduce dentin erosion, as well as Erosion Protection® and TiF4 alone. (AU)

FAPESP's process: 12/20698-0 - Effect of TiF4 on hydroxiapatite and enamel subjected to cariogenic and erosive processes: in vitro and in situ studies
Grantee:Ana Carolina Magalhães
Support Opportunities: Regular Research Grants