| Texto completo | |
| Autor(es): |
Francisco, Cristina de Oliveira
[1]
;
Beltrame, Thomas
[2]
;
Ferraresi, Cleber
[3]
;
Parizotto, Nivaldo Antonio
[1]
;
Bagnato, Vanderlei Salvador
[4]
;
Silva, Audrey Borghi
[1]
;
Benze, Benedito Galvao
[5]
;
Porta, Alberto
[6, 7]
;
Catai, Aparecida Maria
[1]
Número total de Autores: 9
|
| Afiliação do(s) autor(es): | [1] Univ Fed Sao Carlos, Dept Physiotherapy, BR-13565905 Sao Paulo - Brazil
[2] Univ Waterloo, Fac Appl Hlth Sci, Waterloo, ON N2L 3G1 - Canada
[3] Harvard Univ, Sch Med, Massachusetts Gen Hosp, Wellman Ctr Photomed, Boston, MA 02114 - USA
[4] Univ Sao Paulo, Sao Carlos Inst Phys, BR-13566590 Sao Paulo - Brazil
[5] Univ Fed Sao Carlos, Dept Stat, BR-13565905 Sao Paulo - Brazil
[6] Univ Milan, Dept Biomed Sci Hlth, I-20122 Milan - Italy
[7] Policlin San Donato, Dept Cardiothorac Vasc Anesthesia & Intens Care, IRCCS, Milan - Italy
Número total de Afiliações: 7
|
| Tipo de documento: | Artigo Científico |
| Fonte: | Trials; v. 16, DEC 15 2015. |
| Citações Web of Science: | 2 |
| Resumo | |
Background: Type 2 diabetes mellitus (DM) is responsible for a significant reduction in the quality of life due to its negative impact on functional capacity. Cardiopulmonary fitness impairment in DM patients has been associated with limited tissue oxygenation. Phototherapy is widely utilized to treat several disorders due to expected light-tissue interaction. This type of therapy may help to improve muscular oxygenation, thereby increasing aerobic fitness and functional capacity. Methods/Design: This study is a randomized, double-blind, placebo-controlled crossover trial approved by the Ethics Committee of the Federal University of Sao Carlos and registered at ClinicalTrials.gov. Four separate tests will be performed to evaluate the acute effect of phototherapy. All participants will receive both interventions in random order: light-emitting diode therapy (LEDT) and placebo, with a minimum 14-day interval between sessions (washout period). Immediately after the intervention, participants will perform moderate constant workload cycling exercise corresponding to 80 % of the pulmonary oxygen uptake (p(V) over dotO(2)) during the gas exchange threshold (GET). LEDT will be administered with a multidiode cluster probe (50 GaAIA LEDs, 850 eta m, 75 mW each diode, and 3 J per point) before each exercise session. Pulmonary oxygen uptake, muscle oxygenation, heart rate, and arterial pressure will be measured using a computerized metabolic cart, a near-infrared spectrometer, an electrocardiogram, and a photoplethysmography system, respectively. Discussion: The main objective of this study is to evaluate the acute effects of muscular pre-conditioning using LED phototherapy on pulmonary oxygen uptake, muscle oxygenation, heart rate, and arterial pressure dynamics during dynamic moderate exercise. We hypothesize that phototherapy may be beneficial to optimize aerobic fitness in the DM population. Data will be published after the study is completed. (AU) | |
| Processo FAPESP: | 13/07953-3 - Avaliação do efeito agudo da fototerapia por meio de diodos emissores de luz (LEDs) na cinética do consumo de oxigênio muscular e pulmonar em pacientes com diabetes mellitus |
| Beneficiário: | Aparecida Maria Catai |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |
| Processo FAPESP: | 13/08183-7 - Efeito agudo da fototerapia por meio de diodos emissores de luz (LEDs) na cinética do consumo de oxigênio muscular e pulmonar em homens com diabetes mellitus e saudáveis |
| Beneficiário: | Cristina de Oliveira Francisco |
| Modalidade de apoio: | Bolsas no Brasil - Doutorado |