Rhamnolipids know-how: Looking for strategies for its industrial dissemination

Autor(es)

Lovaglio, R. B. ^[1] ; Silva, V. L. ^[1] ; Ferreira, H. ^[1] ; Hausmann, R. ^[2] ; Contiero, J. ^[1]

Afiliação do(s) autor(es)

^[1] UNESP, BR-13506900 Rio Claro, SP - Brazil

^[2] Univ Hohenheim, Sect Bioproc Engn 150K, Inst Food Sci & Biotechnol 150, D-70599 Stuttgart - Germany

• Tipo de documento: Artigo de Revisão
• Fonte: BIOTECHNOLOGY ADVANCES; v. 33, n. 8, p. 1715-1726, DEC 2015.
• Citações Web of Science: 22

Resumo

Despite the numerous advantages of biosurfactants, such as low toxicity, biodegradability and high stability, these compounds are not widely used because of the high cost of production. Details about genetics, regulation and biosynthesis of rhamnolipids by Pseudomonas aeruginosa, are extremely important to the development of bioprocesses involving the synthesis of these compounds. The holding of such knowledge associated with the use of metabolic engineering tools allow modification of producing strains and the development of synthetic routes, with the purpose of increasing the production of rhamnolipids. Considering the need to obtain this know-how, this review provides information on the rhamnolipids, covering genetics, biosynthesis of hydrophobic and hydrophilic portions, and regulation, plus some future strategies that would contribute to the expansion of the production of this green surfactant. (C) 2015 Elsevier Inc. All rights reserved. (AU)

• Processo FAPESP: 12/13452-4 - Avaliação de fluxos metabólicos na complexa rede de produção de ramnolipídios por Pseudomonas aeruginosa
• Beneficiário: Jonas Contiero
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 11/21228-4 - Avaliação de Fluxos Metabólicos na Complexa Rede de Produção de Ramnolipídios por Pseudomonas aeruginosa
• Beneficiário: Roberta Barros Lovaglio
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado