Fate of ivermectin in the terrestrial and aquatic environment: mobility, degradation, and toxicity towards Daphnia similis

Autor(es)

Rath, Susanne ^[1] ; Pereira, Leandro Alves ^[1] ; Dal Bosco, Sandra Maria ^[1] ; Maniero, Milena Guedes ^[2] ; Fostier, Anne Helene ^[1] ; Guimaraes, Jose Roberto ^[2]

Afiliação do(s) autor(es)

^[1] Univ Estadual Campinas, Dept Analyt Chem, Inst Chem, POB 6154, BR-13084971 Campinas, SP - Brazil

^[2] Univ Estadual Campinas, UNICAMP, Sch Civil Engn Architecture & Urban Design, BR-13083852 Campinas, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Environmental Science and Pollution Research; v. 23, n. 6, p. 5654-5666, MAR 2016.
• Citações Web of Science: 1

Resumo

Ivermectin (IVM) is a broad-spectrum antiparasitic drug that is regularly employed in veterinary medicine. In this work, the sorption and desorption of IVM in two Brazilian soils (N1-sand and S2-clay) as well as its leaching capacity, dissipation under aerobic conditions, and degradation in aqueous solution by photocatalysis with TiO2 in suspension were evaluated. The kinetic sorption curves of IVM were adjusted to a pseudo-second-order model. The sorption and desorption data were well fitted with the Freundlich isotherms in the log form (r > 0.96). The Freundlich sorption coefficient (K (F) (ads) ) and the Freundlich desorption coefficient (K (F) (des) ) were 77.7 and 120 mu g(1-1/n) (cm(3))(1/n) g(-1) and 74.5 and 138 mu g(1-1/n) (cm(3))(1/n) g(-1), for soils N1 and S2, respectively. A greater leaching capacity of IVM was observed for the sandy soil N1 than for the clay soil S2. Under aerobic conditions, the dissipation (DT50) at 19.3 A degrees C was 15.5 days (soil N1) and 11.5 days (soil S2). Photocatalysis with UVC and TiO2 in suspension resulted in the degradation of 98 % of IVM (500 mu g L-1) in water in 600 s. The toxicity (Daphnia similis) of the solutions submitted to the photocatalytic process was completely eliminated after 10 min. (AU)

• Processo FAPESP: 13/07817-2 - Degradação de sulfonamidas e tetraciclinas por UV/H2O2 e O3: avaliação da atividade antimicrobiana e da toxicidade
• Beneficiário: Milena Guedes Maniero Ferreira
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado
• Processo FAPESP: 13/09543-7 - Resíduos de medicamentos veterinários no ambiente
• Beneficiário: Susanne Rath
• Modalidade de apoio: Auxílio à Pesquisa - Temático
• Processo FAPESP: 09/17470-4 - Sorção de medicamentos de uso veternário em solos brasileiros
• Beneficiário: Anne Helene Fostier
• Modalidade de apoio: Auxílio à Pesquisa - Regular