Multiple Biomarker Responses in Corbicula fluminea Exposed to Copper in Laboratory Toxicity Tests

Autor(es)

Bonnail, Estefania ^[1] ; Buruaem, Lucas M. ^[2] ; Araujo, Giuliana S. ^[2] ; Abessa, Denis M. S. ^[2] ; Angel DelValls, T. ^[1]

Afiliação do(s) autor(es)

^[1] Univ Cadiz, UNESCO UNITWIN WiCop, Dept Phys Chem, Fac Marine & Environm Sci, Campus Rio San Pedro, Cadiz 11510 - Spain

^[2] Univ Estadual Paulista, Nucleo Estudos Poluicao & Ecotoxicol Aquat, Campus Expt Litoral Paulista, BR-11330900 Sao Vicente, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Archives of Environmental Contamination and Toxicology; v. 71, n. 2, p. 278-285, AUG 2016.
• Citações Web of Science: 9

Resumo

This study evaluated the alteration of the enzymatic system of the freshwater Asian clam exposed to different copper concentrations. Individuals of Corbicula fluminea were exposed to different concentrations of dissolved Cu (0.5, 1, and 2 mg L-1) for 7 days, then, biomarkers of oxidative stress (GST, GPx, GR), exposure (MTs), effect (AChE), and damage (LPO, DNA strand breaks) were quantified. Results showed positive correlations between dissolved metal concentrations and GPx, MTs, and DNA damage, and negative correlation with GST and AChE. In contrast, no clear trend was found for GR and LPO. In general, the established mechanisms of protection might have a beneficial effect on the decreasing ROS attack on membrane and the activation of the metallothioneins. Integrated biomarker analysis revealed that the measured alterations are well correlated with the levels of increasing dissolved copper concentrations in water, demonstrating the effectiveness of this organism for biomonitoring approach purposes. (AU)

• Processo FAPESP: 09/52762-6 - Analise ecotoxicologica e biomonitoramento em bivalves do rio ribeira de iguape - avaliacao da poluicao
• Beneficiário: Denis Moledo de Souza Abessa
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 13/15482-0 - Estabelecimento de valores de referência sítio-específicos para concentrações de contaminantes em sedimentos do litoral do Estado de São Paulo: bases científicas para a criação de uma legislação no âmbito nacional
• Beneficiário: Lucas Buruaem Moreira
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado