Undiagnosed acute HIV infection identified through RNA testing of pooled serum samples obtained during a dengue outbreak in São Paulo, Brazil

Autor(es)

Elaine Monteiro Matsuda ^[1] ; Daniela Rodrigues Colpas ^[2] ; Norberto Camilo Campos ^[3] ; Luana Portes Ozorio Coelho ^[4] ; Andreia Moreira dos Santos Carmo ^[5] ; Luís Fernando de Macedo Brígido ^[6]

Afiliação do(s) autor(es)

^[1] Prefeitura Municipal de Santo André. Programa de Controle das DST/AIDS - Brasil

^[2] Instituto Adolfo Lutz. Governo do Estado de São Paulo. Laboratório Regional - Brasil

^[3] Instituto Adolfo Lutz. Centro de Virologia - Brasil

^[4] Instituto Adolfo Lutz. Centro de Virologia - Brasil

^[5] Instituto Adolfo Lutz. Governo do Estado de São Paulo. Laboratório Regional - Brasil

^[6] Instituto Adolfo Lutz. Centro de Virologia - Brasil

• Tipo de documento: Artigo Científico
• Fonte: Revista da Sociedade Brasileira de Medicina Tropical; v. 50, n. 1, p. 110-112, 2017-02-00.

Resumo

Abstract INTRODUCTION: Improving HIV diagnostics and treatment is necessary to end the AIDS epidemic. Pooled plasma can be used to identify patients with acute HIV disease, even before serological tests. During dengue outbreaks, patients having symptoms common to other acute viral diseases might seek medical care. METHODS: We evaluated HIV RNA in pooled seronegative dengue samples. RESULTS: After excluding individuals with a known HIV diagnosis, an HIV-1 prevalence of 0.73% [95% confidence interval (CI) 0.23-1.76; 4/546 samples] was found. CONCLUSIONS: Promoting strategies to diagnose these individuals and provide them with medical treatment might be instrumental for controlling the HIV epidemic. (AU)

• Processo FAPESP: 13/19441-7 - Identificação e análise de casos incidentes de infecção pelo HIV-1
• Beneficiário: Luís Fernando de Macedo Brígido
• Modalidade de apoio: Auxílio à Pesquisa - Regular