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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Technical aspects and challenges of colorimetric detection with microfluidic paper-based analytical devices (mu PADs) - A review

Texto completo
Autor(es):
Morbioli, Giorgio Gianini ; Mazzu-Nascimento, Thiago ; Stockton, Amanda M. ; Carrilho, Emanuel
Número total de Autores: 4
Tipo de documento: Artigo de Revisão
Fonte: Analytica Chimica Acta; v. 970, p. 1-22, JUN 1 2017.
Citações Web of Science: 66
Resumo

Paper-based devices are a leading alternative among the main analytical tools for point-of-care testing, due to their portability, low-cost, and ease-of-use. Colorimetric readouts are the most common method of detection in these microfluidic devices, enabling qualitative, semi-quantitative and fully quantitative analysis of multiple analytes. There is a multitude of ways to obtain a colorimetric output in such devices, including nanoparticles, dyes, redox and pH indicators, and each has unique drawbacks and benefits. There are also multiple variables that impact the analysis of colorimetric reactions in microfluidic paperbased systems, including color homogeneity, image capture methods, and the data handling itself. Here, we present a critical review of recent developments and challenges of colorimetric detection on microfluidic paper-based analytical devices (mu PADs), and present thoughts and insights towards future perspectives in the area to improve the use of colorimetric readouts in conjunction with mu PADs. (C) 2017 Elsevier B.V. All rights reserved. (AU)

Processo FAPESP: 08/57805-2 - Instituto de Bioanalítica
Beneficiário:Lauro Tatsuo Kubota
Linha de fomento: Auxílio à Pesquisa - Temático
Processo FAPESP: 11/13997-8 - Plataformas em papel para detecção não invasiva de biomarcadores tumorais e para cultivo de células neoplásicas
Beneficiário:Thiago Mazzu Do Nascimento
Linha de fomento: Bolsas no Brasil - Doutorado Direto