| Texto completo | |
| Autor(es): |
Gomes, Willian Robert
;
Devoz, Paula Picoli
;
Araujo, Marilia Ladeira
;
Batista, Bruno Lemos
;
Barbosa, Jr., Fernando
;
Mazzaron Barcelos, Gustavo Rafael
Número total de Autores: 6
|
| Tipo de documento: | Artigo Científico |
| Fonte: | BIOLOGICAL TRACE ELEMENT RESEARCH; v. 178, n. 1, p. 29-35, JUL 2017. |
| Citações Web of Science: | 3 |
| Resumo | |
Lead (Pb) is a toxic metal, frequently associated with occupational exposure, due to its widespread use in industry and several studies have shown high Pb levels in workers occupationally exposed to the metal. The aim of this study was to evaluate the influence of milk and dairy products (MDP) on Pb levels in blood (B-Pb), plasma (P-Pb), and urine (U-Pb), in workers from automotive battery industries in Brazil. The study included 237 male workers; information concerning diet and lifestyle were gathered through a questionnaire, and B-Pb, P-Pb, and U-Pb were determined by ICPMS. Mean B-Pb, P-Pb, and U-Pb were 21 +/- 12, 0.62 +/- 0.73 mu g/dL, and 39 +/- 47 mu g/g creatinine, respectively. Forty three percent of participants declared consuming <= 3 portions/week of MDP (classified as low-MDP intake), while 57% of individuals had >3portions/week of MDP (high-MDP intake). B-Pb and P-Pb were correlated with working time (r(s) = 0.21; r(s) = 0.20; p < 0.010). Multivariable linear regressions showed a significant influence of MDP intake on B-Pb (beta = -0.10; p = 0.012) and P-Pb (beta = -0.16; p < 0.010), while no significance was seen on U-Pb. Our results suggest that MDP consumption may modulate Pb levels in individuals highly exposed to the metal; these findings may be due to the Pb-Ca interactions, since the adverse effects of Pb are partially based on its interference with Ca metabolism and proper Ca supplementation may help to reduce the adverse health effects induced by Pb exposure. (AU) | |
| Processo FAPESP: | 15/04786-4 - Avaliação do estresse oxidativo induzido pela exposição ao chumbo em trabalhadores de fábricas de baterias automotivas |
| Beneficiário: | Willian Robert Gomes |
| Modalidade de apoio: | Bolsas no Brasil - Iniciação Científica |
| Processo FAPESP: | 14/24981-3 - Integração de ferramentas ômicas para o estudo de modelos multivariados nas interações gene-ambiente em população expostas a metais tóxicos |
| Beneficiário: | Gustavo Rafael Mazzaron Barcelos |
| Modalidade de apoio: | Bolsas no Brasil - Jovens Pesquisadores |
| Processo FAPESP: | 13/06033-8 - Integração de ferramentas ômicas para o estudo de modelos multivariados nas interações gene-ambiente em população expostas a metais tóxicos |
| Beneficiário: | Gustavo Rafael Mazzaron Barcelos |
| Modalidade de apoio: | Auxílio à Pesquisa - Jovens Pesquisadores |
| Processo FAPESP: | 15/07277-3 - Avaliação da exposição ao chumbo sobre o padrão de metilação de regiões promotoras de genes relacionados ao metabolismo do metal, em trabalhadores de fábricas de baterias automotivas |
| Beneficiário: | Paula Pícoli Devóz |
| Modalidade de apoio: | Bolsas no Brasil - Mestrado |