Fluoride concentration and amount of dentifrice influence enamel demineralization in situ

Autor(es)

Paiva, M. F. ^[1] ; Delbem, A. C. B. ^[1] ; Danelon, M. ^[1] ; Nagata, M. E. ^[1] ; Moraes, F. R. N. ^[1] ; Coclete, G. E. G. ^[1] ; Cunha, R. F. ^[1] ; Buzalaf, M. A. R. ^[2] ; Pessan, J. P. ^[1]

Afiliação do(s) autor(es)

^[1] Sao Paulo State Univ Unesp, Sch Dent, Dept Pediat Dent & Publ Hlth, Jose Bonifacio 1193, BR-16015050 Aracatuba, SP - Brazil

^[2] Univ Sao Paulo, Bauru Sch Dent, Dept Biol Sci, Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Journal of Dentistry; v. 66, p. 18-22, NOV 2017.
• Citações Web of Science: 5

Resumo

Objectives: This study evaluated the effect of conventional (CD, 1100 ppm F) and low-fluoride (LFD, 550 ppm F) dentifrices, applied in different quantities, on enamel demineralization, and on fluoride (F) concentrations in the dental biofilm formed in situ. Methods: Five combinations of dentifrices and quantities were tested: placebo (P-F-free) applied on all brush bristles; LFD applied by the transversal technique (0.3 g-T1) or on all bristles (0.6 g-T2); and CD applied in a pea-sized amount (0.15 g-T3) or by the transversal technique (0.3 g-T4), in order to produce comparable intensities (F concentration in the dentifrice xamount applied to the brush). Volunteers (n = 13, 20-36 years old) wore palatal devices containing 4 bovine enamel blocks, and performed cariogenic challenges (30% sucrose solution) 6x/day, and brushing 3x/day, following a double-blind, cross-over and randomized protocol. On the 8th day, biofilm was collected 5 and 60 min after brushing. The percentage of surface hardness loss (% SH), integrated loss of subsurface hardness (.KHN) and biofilm F concentrations (solid and fluid phases) were determined. Data were analyzed by repeated-measures ANOVA, Student-Newman-Keuls test, and Pearson's correlation coefficient (p < 0.05). Results: Significantly lower.KHN was observed for treatments with higher intensity (T2 and T4) in comparison with the lower intensity (T1 and T3). A strong correlation was observed between.KHN and F concentrations in total biofilm (r=-0.71) and biofilm fluid (r=-0.72) 5 min after brushing. Conclusions: The treatment intensity has a significant influence on the development of caries lesions in situ. Clinical significance: The intensity of treatment (amount of dentifrice xconcentration) during brushing seems to be a more relevant parameter of clinical efficacy than simply observing the F concentration of the product. The use of a small amount of CD significantly reduced the protective effects against enamel demineralization. (AU)

• Processo FAPESP: 14/16443-1 - Influência da quantidade de dentifrício e concentração de fluoreto na retenção intrabucal de fluoreto em crianças
• Beneficiário: Felipe Ricardo Nunes de Moraes
• Modalidade de apoio: Bolsas no Brasil - Iniciação Científica