Normative values of the Brief Repeatable Battery of Neuropsychological Tests in a Brazilian population sample: discrete and regression-based norms

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Damasceno, Alfredo ^[1] ; Santiago dos Santos Amaral, Juliana Machado ^[2] ; Barreira, Amilton Antunes ^[3] ; Becker, Jefferson ^{[4, 5]} ; Callegaro, Dagoberto ^[6] ; Campanholo, Kenia Repiso ^[6] ; Damasceno, Luciana Azevedo ^[7] ; Diniz, Denise Sisterolli ^[8] ; Fragoso, Yara Dadalti ^[9] ; Franco, Paula S. ^[9] ; Finkelsztejn, Alessandro ^[10] ; Jorge, Frederico M. H. ^[6] ; Lana-Peixoto, Marco Aurelio ^[2] ; da Cunha Matta, Andre Palma ^[7] ; Rabelo Mendonca, Andreia Costa ^[8] ; Noal, Janaina ^[10] ; Paes, Renata Alves ^[11] ; Papais-Alvarenga, Regina Maria ^[11] ; Pereira, Adriana Gutterres ^[5] ; Spedo, Carina Tellaroli ^[3] ; Damasceno, Benito Pereira ^[1]

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^[1] Univ Estadual Campinas, Dept Neurol, Campinas, SP - Brazil

^[2] Univ Fed Minas Gerais, Ctr Invest Esclerose Multipla, Belo Horizonte, MG - Brazil

^[3] Univ Sao Paulo, Fac Med Ribeirao Preto, Hosp Clin Ribeirao Preto, Dept Neurociencias & Ciencias Comportamento, Ribeirao Preto, SP - Brazil

^[4] Pontificia Univ Catolica Rio Grande do Sul, Fac Med, Porto Alegre, RS - Brazil

^[5] Hosp Sao Lucas, Serv Neurol, Porto Alegre, RS - Brazil

^[6] Univ Sao Paulo, Dept Neurol, Sao Paulo, SP - Brazil

^[7] Univ Fed Fluminense, Dept Neurol, Niteroi, RJ - Brazil

^[8] Univ Fed Goias, Hosp Clin, Dept Neurol, Goiania, Go - Brazil

^[9] Univ Metropolitana Santos, Dept Neurol, Santos, SP - Brazil

^[10] Hosp Clin Porto Alegre, Dept Neurol, Porto Alegre, RS - Brazil

^[11] Univ Fed Estado Rio de Janeiro, Dept Neurol, Rio De Janeiro, RJ - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Arquivos de Neuro-Psiquiatria; v. 76, n. 3, p. 163-169, MAR 2018.
• Citações Web of Science: 1

Resumo

Objective: Cognitive dysfunction is common in multiple sclerosis. The Brief Repeatable Battery of Neuropsychological Tests (BRB-N) was developed to assess cognitive functions most-frequently impaired in multiple sclerosis. However, normative values are lacking in Brazil. Therefore, we aimed to provide continuous and discrete normative values for the BRB-N in a Brazilian population sample. Methods: We recruited 285 healthy individuals from the community at 10 Brazilian sites and applied the BRB-N version A in 237 participants and version B in 48 participants. Continuous norms were calculated with multiple-regression analysis. Results: Mean raw scores and the 5th percentile for each neuropsychological measure are provided, stratified by age and educational level. Healthy participants' raw scores were converted to scaled scores, which were regressed on age, sex and education, yielding equations that can be used to calculate predicted scores. Conclusion: Our normative data allow a more widespread use of the BRB-N in clinical practice and research. (AU)

• Processo FAPESP: 16/04270-0 - Avaliação longitudinal da relação entre ausência de atividade de doença e progressão da atrofia cerebral e disfunção cognitiva em pacientes com esclerose múltipla
• Beneficiário: Alfredo Damasceno
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado