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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Normative values of the Brief Repeatable Battery of Neuropsychological Tests in a Brazilian population sample: discrete and regression-based norms

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Author(s):
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Damasceno, Alfredo [1] ; Santiago dos Santos Amaral, Juliana Machado [2] ; Barreira, Amilton Antunes [3] ; Becker, Jefferson [4, 5] ; Callegaro, Dagoberto [6] ; Campanholo, Kenia Repiso [6] ; Damasceno, Luciana Azevedo [7] ; Diniz, Denise Sisterolli [8] ; Fragoso, Yara Dadalti [9] ; Franco, Paula S. [9] ; Finkelsztejn, Alessandro [10] ; Jorge, Frederico M. H. [6] ; Lana-Peixoto, Marco Aurelio [2] ; da Cunha Matta, Andre Palma [7] ; Rabelo Mendonca, Andreia Costa [8] ; Noal, Janaina [10] ; Paes, Renata Alves [11] ; Papais-Alvarenga, Regina Maria [11] ; Pereira, Adriana Gutterres [5] ; Spedo, Carina Tellaroli [3] ; Damasceno, Benito Pereira [1]
Total Authors: 21
Affiliation:
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[1] Univ Estadual Campinas, Dept Neurol, Campinas, SP - Brazil
[2] Univ Fed Minas Gerais, Ctr Invest Esclerose Multipla, Belo Horizonte, MG - Brazil
[3] Univ Sao Paulo, Fac Med Ribeirao Preto, Hosp Clin Ribeirao Preto, Dept Neurociencias & Ciencias Comportamento, Ribeirao Preto, SP - Brazil
[4] Pontificia Univ Catolica Rio Grande do Sul, Fac Med, Porto Alegre, RS - Brazil
[5] Hosp Sao Lucas, Serv Neurol, Porto Alegre, RS - Brazil
[6] Univ Sao Paulo, Dept Neurol, Sao Paulo, SP - Brazil
[7] Univ Fed Fluminense, Dept Neurol, Niteroi, RJ - Brazil
[8] Univ Fed Goias, Hosp Clin, Dept Neurol, Goiania, Go - Brazil
[9] Univ Metropolitana Santos, Dept Neurol, Santos, SP - Brazil
[10] Hosp Clin Porto Alegre, Dept Neurol, Porto Alegre, RS - Brazil
[11] Univ Fed Estado Rio de Janeiro, Dept Neurol, Rio De Janeiro, RJ - Brazil
Total Affiliations: 11
Document type: Journal article
Source: Arquivos de Neuro-Psiquiatria; v. 76, n. 3, p. 163-169, MAR 2018.
Web of Science Citations: 1
Abstract

Objective: Cognitive dysfunction is common in multiple sclerosis. The Brief Repeatable Battery of Neuropsychological Tests (BRB-N) was developed to assess cognitive functions most-frequently impaired in multiple sclerosis. However, normative values are lacking in Brazil. Therefore, we aimed to provide continuous and discrete normative values for the BRB-N in a Brazilian population sample. Methods: We recruited 285 healthy individuals from the community at 10 Brazilian sites and applied the BRB-N version A in 237 participants and version B in 48 participants. Continuous norms were calculated with multiple-regression analysis. Results: Mean raw scores and the 5th percentile for each neuropsychological measure are provided, stratified by age and educational level. Healthy participants' raw scores were converted to scaled scores, which were regressed on age, sex and education, yielding equations that can be used to calculate predicted scores. Conclusion: Our normative data allow a more widespread use of the BRB-N in clinical practice and research. (AU)

FAPESP's process: 16/04270-0 - A longitudinal evaluation of the relationship between no evidence of disease activity and progression of cerebral atrophy and cognitive dysfunction in patients with multiple sclerosis
Grantee:Alfredo Damasceno
Support Opportunities: Scholarships in Brazil - Post-Doctoral