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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Influence of Obstructive Sleep Apnea in the Functional Aspects of Patients With Osteoarthritis

Texto completo
Autor(es):
Silva, Andressa [1] ; Mello, Marco Tulio [1] ; Serrao, Paula Regina [2] ; Luz, Roberta Pitta [3] ; Ruiz, Franciele [3] ; Bittencourt, Lia Rita [3] ; Tufik, Sergio [3] ; Mattiello, Stela Marcia [2]
Número total de Autores: 8
Afiliação do(s) autor(es):
[1] Univ Fed Minas Gerais, Belo Horizonte, MG - Brazil
[2] Univ Fed Sao Carlos UFSCAR, Sao Carlos, SP - Brazil
[3] Univ Fed Sao Paulo UNIFESP, Sao Paulo - Brazil
Número total de Afiliações: 3
Tipo de documento: Artigo Científico
Fonte: JOURNAL OF CLINICAL SLEEP MEDICINE; v. 14, n. 2, p. 265-270, 2018.
Citações Web of Science: 1
Resumo

Study Objectives: It has been demonstrated in recent studies that obstructive sleep apnea (OSA) is the most prevalent sleep disorder in patients with osteoarthritis (OA), and thus the current study aimed to investigate the influence of OSA on knee extensor torque, pain, stiffness, and physical function in men with low-grade knee OA. Methods: The study included 60 male volunteers, aged 40 to 70 years, allocated into four groups: Group 1 (G1) Control (n = 15): without OA and without OSA; Group 2 (G2) (n = 15): with OA and without OSA; Group 3 (G3) (n = 15): without OA and with OSA; and Group 4 (G4) (n = 15) with OA and with OSA. All volunteers were examined using knee radiographs and polysomnography, responded to the Western Ontario McMaster Osteoarthritis Index (WOMAC) questionnaire, and completed a test on an isokinetic dynamometer to evaluate peak isometric knee extensor torque, both concentric and eccentric (90 degrees/s and 180 degrees/s). Results: Regarding the data from the WOMAC questionnaire (for pain, stiffness, and physical function), it was observed that G4 showed higher values compared to G1 or G3. For the concentric isometric and isokinetic peak knee extensor torque, lower values were observed in G4 compared to G1 or G3. Conclusions: Patients who have knee OA in the early grades, when associated with OSA, have higher changes of the peak extensor torque, pain, stiffness, and physical function, compared with patients who did not have OSA. (AU)

Processo FAPESP: 10/19437-1 - Influência da Síndrome da Apnéia Obstrutiva do Sono sobre os aspectos funcionais e inflamatórios de indivíduos com osteoartrite de joelho
Beneficiário:Andressa da Silva de Mello
Linha de fomento: Bolsas no Brasil - Doutorado
Processo FAPESP: 11/06619-7 - Influência das alterações de sono no controle sensório-motor e na resposta inflamatória sistêmica em pacientes com osteoartrite de joelho graus I ou II
Beneficiário:Stela Márcia Mattiello
Linha de fomento: Auxílio à Pesquisa - Regular