Influence of Obstructive Sleep Apnea in the Functional Aspects of Patients With Osteoarthritis

Author(s)

Silva, Andressa ^[1] ; Mello, Marco Tulio ^[1] ; Serrao, Paula Regina ^[2] ; Luz, Roberta Pitta ^[3] ; Ruiz, Franciele ^[3] ; Bittencourt, Lia Rita ^[3] ; Tufik, Sergio ^[3] ; Mattiello, Stela Marcia ^[2]

Affiliation

^[1] Univ Fed Minas Gerais, Belo Horizonte, MG - Brazil

^[2] Univ Fed Sao Carlos UFSCAR, Sao Carlos, SP - Brazil

^[3] Univ Fed Sao Paulo UNIFESP, Sao Paulo - Brazil

• Document type: Journal article
• Source: JOURNAL OF CLINICAL SLEEP MEDICINE; v. 14, n. 2, p. 265-270, 2018.
• Web of Science Citations: 1

Abstract

Study Objectives: It has been demonstrated in recent studies that obstructive sleep apnea (OSA) is the most prevalent sleep disorder in patients with osteoarthritis (OA), and thus the current study aimed to investigate the influence of OSA on knee extensor torque, pain, stiffness, and physical function in men with low-grade knee OA. Methods: The study included 60 male volunteers, aged 40 to 70 years, allocated into four groups: Group 1 (G1) Control (n = 15): without OA and without OSA; Group 2 (G2) (n = 15): with OA and without OSA; Group 3 (G3) (n = 15): without OA and with OSA; and Group 4 (G4) (n = 15) with OA and with OSA. All volunteers were examined using knee radiographs and polysomnography, responded to the Western Ontario McMaster Osteoarthritis Index (WOMAC) questionnaire, and completed a test on an isokinetic dynamometer to evaluate peak isometric knee extensor torque, both concentric and eccentric (90 degrees/s and 180 degrees/s). Results: Regarding the data from the WOMAC questionnaire (for pain, stiffness, and physical function), it was observed that G4 showed higher values compared to G1 or G3. For the concentric isometric and isokinetic peak knee extensor torque, lower values were observed in G4 compared to G1 or G3. Conclusions: Patients who have knee OA in the early grades, when associated with OSA, have higher changes of the peak extensor torque, pain, stiffness, and physical function, compared with patients who did not have OSA. (AU)

• FAPESP's process: 11/06619-7 - Influence of changes of sleep in sensory-motor control and systemic inflammatory response in patients with knee osteoarthritis of grade I or II
• Grantee: Stela Márcia Mattiello
• Support Opportunities: Regular Research Grants
• FAPESP's process: 10/19437-1 - INFLUENCE OF OBSTRUCTIVE SLEEP APNEA SYNDROME ON INFLAMMATORY AND FUNCTIONAL ASPECTS OF INDIVIDUALS WITH KNEE OSTEOARTHRITIS
• Grantee: Andressa da Silva de Mello
• Support Opportunities: Scholarships in Brazil - Doctorate