CuO Nanoparticles as An Efficient Heterogeneous Catalyst for the 1,3-Dipolar Cycloaddition of Dicarbonyl Compounds to Azides

Autor(es)

Dias, Cassio da S. ^{[1, 2]} ; Lima, Thiago de M. ^{[1, 3]} ; Lima, Carolina G. S. ^[1] ; Zuekrman-Schpector, Julio ^[4] ; Schwab, Ricardo S. ^[1]

Afiliação do(s) autor(es)

^[1] Univ Fed Sao Carlos, Dept Quim, Ctr Excellence Res Sustainable Chem CERSusChem, Rodovia Washington Luis, Km 235 SP 310, BR-13565905 Sao Carlos, SP - Brazil

^[2] Inst Fed Maranhao, Dept Ensino, Campus Acailandia, Av Projetada, S-N, BR-65930000 Acailandia, MA - Brazil

^[3] Univ Fed Fluminense, Dept Quim Inorgan, Campus Valonguinho, Outeiro San Jose Batista S-N, BR-24020150 Niteroi, RJ - Brazil

^[4] Univ Fed Sao Carlos, Dept Quim, Sao Carlos, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: CHEMISTRYSELECT; v. 3, n. 22, p. 6195-6202, JUN 15 2018.
• Citações Web of Science: 3

Resumo

Substituted 1,2,3-triazoles are important heterocyclic molecules with applications in diverse research areas. The organocatalytic (3+2) cycloaddition reaction of azides with active methylene compounds has proven to be a powerful strategy for the synthesis of a variety of 1,2,3-triazoles with different substituents. However the reported methods in the literature, commonly used a homogenous organocatalyst. Considering this point, here we have reported a novel heterogeneous protocol for the synthesis of 1,4,5-trisubstituted 1,2,3-triazoles by reaction of different dicarbonyl compounds with aryl azides catalyzed by copper oxide nanoparticles under microwave irradiation. The important features of this methodology are high yield products, short reaction times and recyclability of the CuO catalyst. (AU)

• Processo FAPESP: 17/06536-0 - Química verde: métodos sintéticos sustentáveis que utilizam catálise, solventes benignos, reagentes mais seguros e feedstock bio-renovável
• Beneficiário: Thiago de Melo Lima
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado
• Processo FAPESP: 13/06558-3 - Catálise metálica assimétrica: preparação de alcoóis quirais e seus derivados a partir de reagentes orgânicos de zinco poli-funcionalizados e aplicação de novos ligantes quirais suportados em nanopartículas magnéticas
• Beneficiário: Ricardo Samuel Schwab
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 14/50249-8 - Green chemistry: sustainable synthetic methods employing benign solvents, safer reagents, and bio-renewable feedstock
• Beneficiário: Arlene Gonçalves Corrêa
• Modalidade de apoio: Auxílio à Pesquisa - Programa Centros de Pesquisa em Engenharia