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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Dynapenic obesity as an associated factor to lipid and glucose metabolism disorders and metabolic syndrome in older adults - Findings from SABE Study

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Autor(es):
Alexandre, Tiago da Silva [1, 2] ; Aubertin-Leheudre, Mylene [3] ; Carvalho, Livia Pinheiro [4] ; Maximo, Roberta de Oliveira [4] ; Corona, Ligiana Pires [5] ; Pereira de Brito, Tabatta Renata [6] ; Nunes, Daniella Pires [7] ; Ferreira Santos, Jair Licio [8] ; de Oliveira Duarte, Yeda Aparecida [9] ; Lebrao, Maria Lucia [10]
Número total de Autores: 10
Afiliação do(s) autor(es):
[1] UCL, Dept Epidemiol & Publ Hlth, London - England
[2] Univ Fed Sao Carlos, Gerontol Dept, Rodovia Washington Luis, Km 235, SP-310, BR-13565905 Sao Carlos, SP - Brazil
[3] Dept Sci Phys Act, Montreal, PQ - Canada
[4] Univ Fed Sao Carlos, Phys Therapy Dept, Sao Carlos, SP - Brazil
[5] Univ Estadual Campinas, Fac Sci Appl, Limeira - Brazil
[6] Univ Fed Alfenas, Fac Nutr, Alfenas - Brazil
[7] Fed Univ Tocantins, Dept Nursing, Tocantins - Brazil
[8] Univ Sao Paulo, Dept Social Med, Ribeirao Preto - Brazil
[9] Univ Sao Paulo, Dept Med Surg Nursing, Sao Paulo - Brazil
[10] Univ Sao Paulo, Dept Epidemiol, Sao Paulo - Brazil
Número total de Afiliações: 10
Tipo de documento: Artigo Científico
Fonte: Clinical Nutrition; v. 37, n. 4, p. 1360-1366, AUG 2018.
Citações Web of Science: 3
Resumo

Background \& aims: There is little evidence showing that dynapenic obesity is associated with lipid and glucose metabolism disorders, high blood pressure, chronic disease and metabolic syndrome. Our aim was to analyze whether dynapenic abdominal obesity can be associated with lipid and glucose metabolism disorders, high blood pressure, metabolic syndrome and cardiovascular diseases in older adults living in sao Paulo. Methods: This cross-sectional study included 833 older adults who took part of the third wave of the Health, Well-being and Aging Study in 2010. Based on waist circumference (>88 cm women and >102 cm men) and handgrip strength (<16 kg women and <26 kg men), four groups were identified: nondynapenic/non-abdominal obese (ND/NAO), abdominal obese alone (AOA), dynapenic alone (DA) and dynapenic/abdominal obese (D/AO). Dependent variables were blood pressure, lipid profile, fasting glucose and glycated-haemoglobin, metabolic syndrome and cardiovascular diseases. Logistic regression was used to analyze the associations between dynapenia and abdominal obesity status and lipid and glucose metabolic profiles, blood pressure, cardiovascular diseases and metabolic syndrome. Results: The fully adjusted models showed that D/AO individuals had higher prevalence of low HDL plasma concentrations (OR = 2.51, 95%CI: 1.40-4.48), hypertriglyceridemia (OR = 2.53, 95%CI: 1.43 -4.47), hyperglycemia (OR = 2.05, 95%CI: 1.14-3.69), high glycated-haemoglobin concentrations (OR = 1.84, 95%CI: 1.03-3.30) and metabolic syndrome (OR = 12.39, 95%CI: 7.38-20.79) than ND/NAO. Dynapenic and D/AO individuals had higher prevalence of heart disease (OR = 2.05, 95%CI: 1.17-3.59 and OR = 1.92, 95%CI: 1.06-3.48, respectively) than ND/NAO. Conclusion: D/AO was associated with high prevalence of lipid and glucose metabolism disorders and metabolic syndrome while dynapenia and D/AO were associated with high prevalence of heart disease. (C) 2017 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved. (AU)

Processo FAPESP: 09/53778-3 - Estudo longitudinal sobre as condições de vida e saúde dos idosos do município de São Paulo - estudo SABE
Beneficiário:Maria Lúcia Lebrão
Linha de fomento: Auxílio à Pesquisa - Temático