| Texto completo | |
| Autor(es): |
Teixeira, Renata Nakata
[1]
;
Leite, Gerson dos Santos
[1]
;
Gorjao, Renata
[2]
;
Palmeira, Patricia
[3]
;
Momesso Santos, Cesar Miguel
[2]
;
Zambonatto, Raquel
[2]
;
de Oliveira, Heloisa Helena
[2]
;
Levada, Adriana Cristina
[2]
;
Fiks, Iara Nely
[4]
;
Fernandes Carvalho, Celso Ricardo
[1]
Número total de Autores: 10
|
| Afiliação do(s) autor(es): | [1] Univ Sao Paulo, Dept Phys Therapy, Sao Paulo, SP - Brazil
[2] Univ Cruzeiro Sul, Postgrad Program Human Movement Sci, Inst Phys Act Sci & Sports, Sao Paulo - Brazil
[3] Univ Sao Paulo, Sch Med, Sao Paulo - Brazil
[4] Univ Sao Paulo, Heart Inst InCor, Pulm Div, Sao Paulo - Brazil
Número total de Afiliações: 4
|
| Tipo de documento: | Artigo Científico |
| Fonte: | INTERNATIONAL JOURNAL OF SPORTS MEDICINE; v. 39, n. 9, p. 720-725, SEP 2018. |
| Citações Web of Science: | 1 |
| Resumo | |
The present study aimed to compare the immune and inflammatory responses between atopic (n = 20) and non-atopic (n =39) elite endurance athletes. Fifty-nine elite runners and triathletes were assessed for the following measurements: Th-1, Th-2 and lymphocyte phenotyping and plasma levels of cortisol, chemokines, inflammatory cytokines and specific immunoglobulin E (IgE). Levels of salivary IgA, allergic symptoms and training data were also evaluated. No difference was observed in baseline lymphocyte levels. However, the Th-1 lymphocytes of atopic athletes presented a lower response after activation. In contrast to this result, levels of salivary IgA and CXCL9 chemokine were higher in the atopic athletes. It was observed that the volume of training per week was linearly associated with Th-1 levels, allergic symptoms and IgE levels. In addition, linear multiple regression analysis demonstrated that the volume of training was the only factor associated with allergic symptoms in atopic athletes (r = 0.53; p = 0.04). These results suggest that compared to non-atopic athletes, atopic athletes present a reduced Th-1 response and higher levels of salivary IgA. Training volume is associated with the immune response and allergic symptoms, which suggests that they may play a role in the atopy in elite endurance athletes. (AU) | |
| Processo FAPESP: | 14/02915-9 - Resposta imune e sintomas alérgicos e respiratórios em atletas de alto rendimento: validação de marcadores e efeito do tratamento clínico no desempenho esportivo |
| Beneficiário: | Renata Nakata Teixeira |
| Modalidade de apoio: | Bolsas no Brasil - Pós-Doutorado |