Can the antral follicular count modulate the gene expression of bovine oviducts in Aberdeen Angus and Nelore heifers?

Autor(es)

Fontes, Patricia Kubo ^[1] ; Ereno, Ronaldo Luis ^[1] ; Peixoto, Andre Rebello ^[2] ; Carvalho, Robson Francisco ^[2] ; Scarano, Wellerson Rodrigo ^[2] ; Trinca, Luzia Aparecida ^[3] ; Barros, Ciro Moraes ^[1] ; de Souza Castilho, Anthony Cesar ^[4]

Afiliação do(s) autor(es)

^[1] Univ Estadual Paulista UNESP, Inst Biosci, Dept Pharmacol, Botucatu, SP - Brazil

^[2] Univ Estadual Paulista UNESP, Inst Biosci, Dept Morphol, Botucatu, SP - Brazil

^[3] Univ Estadual Paulista UNESP, Inst Biosci, Dept Biostat, Botucatu, SP - Brazil

^[4] Univ Western Sao Paulo UNOESTE, Dept Anim Sci, Presidente Prudente, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: PLoS One; v. 13, n. 8 AUG 29 2018.
• Citações Web of Science: 3

Resumo

The number of visible ovarian antral follicles (antral follicle count D AFC) is repeatable in bovine individuals, but highly variable between animals, and with differences between Bos taurus and Bos indicus breeds. Several studies have tried to determine the correlation between AFC and increased fertility in cattle. While the impacts of AFC on embryo production, hormonal levels, and pregnancy rates have been described, the molecular effects of AFC on bovine oviducts have not yet been investigated. Here, the aim was to investigate the impact of breeds, such as Aberdeen Angus and Nelore heifer with high or low AFC, on abundance of transcripts and protein related to oviductal transport, sperm reservoir formation, monospermy control, and gamete interaction in the oviducts. In summary, the ovulation side was the major factor that affected transcript abundance on bovine oviducts. However, a discreet effect among AFC and cattle breeds was also observed. Based on this, we concluded and reinforced here that differential microenvironments between ipsilateral and contralateral oviducts have a major effect on modulating the transcripts related to oviductal transport, sperm reservoir formation, monospermy control, and gamete interaction. However, we cannot exclude that there is minimal effect of AFC or breed on regulation of some genes (such as AGTR1, ACE1, FUCA1, and VEGFA) in bovine oviducts. (AU)

• Processo FAPESP: 13/08629-5 - Perfil de expressão proteica em tecidos reprodutivos bovinos
• Beneficiário: Patricia Kubo Fontes
• Modalidade de apoio: Bolsas no Exterior - Estágio de Pesquisa - Mestrado
• Processo FAPESP: 12/09498-9 - Influência da raça (Nelore e Angus) e da população folicular sobre o perfil de genes diferencialmente expressos em ovidutos bovinos
• Beneficiário: Patricia Kubo Fontes
• Modalidade de apoio: Bolsas no Brasil - Mestrado
• Processo FAPESP: 11/50964-0 - Estudo comparativo da populacao folicular de vacas nelore e angus
• Beneficiário: Ciro Moraes Barros
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 12/50514-8 - Influencia da raca (nelore e angus) e da populacao folicular sobre o perfil de genes diferencialmente expressos em ovidutos bovinos.
• Beneficiário: Ciro Moraes Barros
• Modalidade de apoio: Auxílio à Pesquisa - Regular