Supramolecular DNA origami nanostructures for use in bioanalytical applications

Autor(es)

Kogikoski, Jr., Sergio ^[1] ; Paschoalino, Waldemir J. ^[1] ; Kubota, Lauro T. ^[1]

Afiliação do(s) autor(es)

^[1] State Univ Campinas UNICAMP, Inst Chem, Dept Analyt Chem, POB 6154, BR-13083970 Campinas, SP - Brazil

• Tipo de documento: Artigo de Revisão
• Fonte: TRAC-TRENDS IN ANALYTICAL CHEMISTRY; v. 108, p. 88-97, NOV 2018.
• Citações Web of Science: 6

Resumo

Bioanalytical chemistry is defined as the study of biological molecules and their related processes, and in the last two decades, it has advanced considerably due to the development of a variety of techniques and general nanotechnological progress. One technique for creating analytical nanodevices that has appeared recently is DNA origami, which uses DNA programmability to create nanostructures with high shape, size and actuation fidelity. Due to its versatility, this technique can be used to develop functional bioanalytical devices, and it is one of the keys to advancing analytical chemistry applications towards single-molecule studies. Herein, we briefly review the field of DNA nanotechnology and some reasons for the widespread attention to this topic from the scientific community. Later, perspectives and applications related to the field of analytical chemistry will be discussed, focusing principally on recent advances in the development of DNA devices for bioanalytical chemistry studies and DNA-based nanomachines. (c) 2018 Elsevier B.V. All rights reserved. (AU)

• Processo FAPESP: 16/14507-8 - Estudos das Propriedades Estruturais e Eletroquímicas de Filmes Nanoestruturados baseados em DNA
• Beneficiário: Sergio Kogikoski Junior
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado
• Processo FAPESP: 14/50867-3 - INCT 2014: Instituto Nacional de Ciência e Tecnologia de Bioanalítica
• Beneficiário: Marco Aurelio Zezzi Arruda
• Modalidade de apoio: Auxílio à Pesquisa - Temático
• Processo FAPESP: 13/22127-2 - Desenvolvimento de novos materiais estratégicos para dispositivos analíticos integrados
• Beneficiário: Lauro Tatsuo Kubota
• Modalidade de apoio: Auxílio à Pesquisa - Temático
• Processo FAPESP: 17/05213-3 - Avaliação da atividade eletrocatalítica de sensores baseados em óxido de grafeno decorados com nanopartículas de Pt, Au e Ag por microscopia eletroquímica de varredura.
• Beneficiário: Waldemir José Paschoalino Junior
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado