| Texto completo | |
| Autor(es): |
Duarte, Poliana Mendes
[1]
;
Feres, Magda
[1]
;
Smeili Yassine, Lina Lameh
[1]
;
Silva Soares, Geisla Mary
[2]
;
Miranda, Tamires Szeremeske
[1]
;
Faveri, Marcelo
[1]
;
Retamal-Valdes, Belen
[1]
;
Figueiredo, Luciene Cristina
[1]
Número total de Autores: 8
|
| Afiliação do(s) autor(es): | [1] Univ Guarulhos, Dent Res Div, Dept Periodontol, Sao Paulo - Brazil
[2] Univ Fed Parana, Dept Stomatol, Curitiba, Parana - Brazil
Número total de Afiliações: 2
|
| Tipo de documento: | Artigo Científico |
| Fonte: | JOURNAL OF CLINICAL PERIODONTOLOGY; v. 45, n. 11, p. 1326-1335, NOV 2018. |
| Citações Web of Science: | 0 |
| Resumo | |
Aim To evaluate if non-diabetic subjects with periodontitis respond better than subjects with type 2 diabetes to the treatment protocol of scaling and root planing (SRP), metronidazole (MTZ) and amoxicillin (AMX). Material and Methods Results Diabetic and nondiabetic subjects with severe periodontitis received SRP + MTZ (400 mg/thrice a day {[}TID]) + AMX (500 mg/TID) for 14 days. Subgingival biofilm samples were analyzed by checkerboard DNA-DNA hybridization for 40 bacterial species. Subjects were monitored at baseline, 3, 6 and 12 months post-therapy. Twenty-nine type 2 diabetics and 29 non-diabetic subjects participated of this study. Of the non-diabetics and diabetics, 68.9% and 75.9%, respectively, reached the clinical endpoint for treatment (<= 4 sites with probing depth {[}PD] >= 5 mm) at 1 year post-therapy (p > 0.05). The diabetic group presented lower mean clinical attachment gain from baseline to 1 year post-therapy and higher mean proportions of the red and orange complexes than the non-diabetic group (p < 0.05). Conclusions Non-diabetic subjects with severe periodontitis did not respond better than type 2 diabetic subjects to the treatment protocol of SRP + MTZ + AMX, both in terms of achieving the clinical endpoint for treatment and of PD improvement. Diabetic subjects exhibited a slightly worse microbiological response and showed a healing process more associated with gingival recession than the non-diabetics. (AU) | |
| Processo FAPESP: | 11/14872-4 - Metronidazol e amoxicilina sistêmicos adjunto à raspagem e alisamento radicular no tratamento de periodontite crônica em diabéticos tipo 2: avaliação clínica, glicêmica e microbiológica. |
| Beneficiário: | Tamires Szeremeske de Miranda |
| Modalidade de apoio: | Bolsas no Brasil - Mestrado |
| Processo FAPESP: | 07/55291-9 - Associacao de antibioticoterapia e do controle quimico da placa supragengival ao tratamento periodontal mecanico. avaliacao clinica e microbiologica. |
| Beneficiário: | Luciene Cristina de Figueiredo |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |
| Processo FAPESP: | 13/01072-5 - Metronidazol e amoxicilina sistêmicos adjunto à raspagem e alisamento radicular no tratamento de periodontite crônica em diabéticos tipo 2: avaliações clínicas, glicêmicas e microbiológicas. |
| Beneficiário: | Poliana Mendes Duarte |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |