New insights of Raman spectroscopy for oral clinical applications

Autor(es)

das Chagas e Silva de Carvalho, Luis Felipe ^{[1, 2]} ; Nogueira, Marcelo Saito ^[3]

Afiliação do(s) autor(es)

^[1] Univ Taubate, Dept Odontol, Taubate - Brazil

^[2] Ctr Univ Braz Cubas, Mogi Das Cruzes - Brazil

^[3] Univ Coll Cork, Tyndall Natl Inst, Lee Maltings Complex Dyke Parade, Cork T12R5CP - Ireland

• Tipo de documento: Artigo Científico
• Fonte: ANALYST; v. 143, n. 24, p. 6037-6048, DEC 21 2018.
• Citações Web of Science: 2

Resumo

Oral injuries are currently diagnosed by histopathological analysis of biopsy, which is an invasive procedure and does not give immediate results. On the other hand, the Raman spectroscopy technique is a real-time and minimally invasive analytical tool with a notable diagnostic capability. At the current stage, researchers are widely aware of the diagnostic potential of the technique and how it is considered promising for providing biochemical information in real time and without damaging the tissue. The problem originates from a lack of relevant studies and clinical trials that could show the actual use of Raman spectroscopy to help patients. Our goal here is to narrow the relationship between physicists, chemists, engineers, computer scientists, and the medical community, and in fact discuss the potential of Raman spectroscopy as a novel clinical analysis method. In the present study, we focused on the use of Raman spectroscopy as a daily clinical practice. In this context, additional studies and in vivo tests should be performed with the same approach as a real application. We want to show the scientific and industrial community what is really necessary for this, starting from a clinical point of view. Using our previous experience publishing different oral pathologies and types of samples, we also aim to discuss the current state and potential of Raman spectroscopy and what is required to implement Raman spectroscopy for oral clinical applications. (AU)

• Processo FAPESP: 18/03636-7 - 10a Conferência SPEC 2018
• Beneficiário: Luis Felipe das Chagas e Silva de Carvalho
• Modalidade de apoio: Auxílio à Pesquisa - Reunião - Exterior
• Processo FAPESP: 14/05978-1 - Utilização da espectroscopia Raman in vivo para diagnóstico de processos patológicos bucais
• Beneficiário: Luis Felipe das Chagas e Silva de Carvalho
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado