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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

New insights of Raman spectroscopy for oral clinical applications

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Author(s):
das Chagas e Silva de Carvalho, Luis Felipe [1, 2] ; Nogueira, Marcelo Saito [3]
Total Authors: 2
Affiliation:
[1] Univ Taubate, Dept Odontol, Taubate - Brazil
[2] Ctr Univ Braz Cubas, Mogi Das Cruzes - Brazil
[3] Univ Coll Cork, Tyndall Natl Inst, Lee Maltings Complex Dyke Parade, Cork T12R5CP - Ireland
Total Affiliations: 3
Document type: Journal article
Source: ANALYST; v. 143, n. 24, p. 6037-6048, DEC 21 2018.
Web of Science Citations: 2
Abstract

Oral injuries are currently diagnosed by histopathological analysis of biopsy, which is an invasive procedure and does not give immediate results. On the other hand, the Raman spectroscopy technique is a real-time and minimally invasive analytical tool with a notable diagnostic capability. At the current stage, researchers are widely aware of the diagnostic potential of the technique and how it is considered promising for providing biochemical information in real time and without damaging the tissue. The problem originates from a lack of relevant studies and clinical trials that could show the actual use of Raman spectroscopy to help patients. Our goal here is to narrow the relationship between physicists, chemists, engineers, computer scientists, and the medical community, and in fact discuss the potential of Raman spectroscopy as a novel clinical analysis method. In the present study, we focused on the use of Raman spectroscopy as a daily clinical practice. In this context, additional studies and in vivo tests should be performed with the same approach as a real application. We want to show the scientific and industrial community what is really necessary for this, starting from a clinical point of view. Using our previous experience publishing different oral pathologies and types of samples, we also aim to discuss the current state and potential of Raman spectroscopy and what is required to implement Raman spectroscopy for oral clinical applications. (AU)

FAPESP's process: 18/03636-7 - 10th Conference SPEC 2018
Grantee:Luis Felipe das Chagas e Silva de Carvalho
Support Opportunities: Research Grants - Meeting - Abroad
FAPESP's process: 14/05978-1 - In vivo Raman spectroscopy for pathological processes of oral mucosa diagnosis
Grantee:Luis Felipe das Chagas e Silva de Carvalho
Support Opportunities: Scholarships in Brazil - Post-Doctoral