International high-risk clonal lineages of CTX-M-producing Escherichia coli F-ST648 in free-roaming cats, South America

Autor(es)

Fernandes, Miriam R. ^[1] ; Sellera, Fabio P. ^[2] ; Moura, Quezia ^[3] ; Gaspar, Vitor C. ^[2] ; Cerdeira, Louise ^[1] ; Lincopan, Nilton ^{[3, 1]}

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Sch Pharmaceut Sci, Dept Clin & Toxicol Anal, Sao Paulo - Brazil

^[2] Univ Sao Paulo, Sch Vet Med & Anim Sci, Dept Internal Med, Sao Paulo - Brazil

^[3] Univ Sao Paulo, Inst Biomed Sci, Dept Microbiol, Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: INFECTION GENETICS AND EVOLUTION; v. 66, p. 48-51, DEC 2018.
• Citações Web of Science: 2

Resumo

The dissemination of extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli belonging to high-virulent pandemic lineages has become a global problem with serious consequences for public health worldwide. In this regard, E. coli lineages belonging to the sequence type ST648, which are mostly associated with human infections, have begun to be reported in animals. In this study, we report the identification and genomic characterization of international CTX-M-producing E. coli ST648/F lineages in free-roaming cats from an urban slum, in Brazil. Moreover, we have performed a comparative genomic analysis of worldwide reported E. coli ST648 strains, highlighting an epidemiologic linkage between human and companion animals. (AU)

• Processo FAPESP: 15/13527-2 - Relação ancestral, pan-resistoma plasmidial de Escherichia coli produtora de b-lactamases de espectro estendido (CTX-M) e métodos de cura plasmidial
• Beneficiário: Miriam Rodriguez Fernandes
• Modalidade de apoio: Bolsas no Brasil - Doutorado