Brotasic Acid Methyl Ester from the Fruiting Bodies of the Mushroom Auricularia sp

Autor(es)

Slivinski, Juliano ^[1] ; Santos, Mario F. C. ^[2] ; Ferreira, Antonio G. ^[3] ; Berlinck, Roberto G. S. ^[1]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Inst Quim Sao Carlos, CP 780, BR-13560970 Sao Carlos, SP - Brazil

^[2] Univ Fed Alfenas, Inst Quim, BR-37130001 Alfenas, MG - Brazil

^[3] Univ Fed Sao Carlos, Dept Quim, Rodovia Washington Luis S-N, Km 235, Sao Carlos, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: PHYTOCHEMISTRY LETTERS; v. 29, p. 91-93, FEB 2019.
• Citações Web of Science: 0

Resumo

Mushroom alkaloids are of a considerable interest as a consequence of their unique secondary metabolites. This work describes the isolation and identification of brotasic acid methyl ester (1) from the fruiting bodies of the mushroom Auricularia sp. After isolation using a series of chromatographic steps, compound 1 was identified by analysis of spectroscopic data and has a novel carbon skeleton. The structure of 1 is related to the structure of the histone deacetylase inhibitor SAHA. (AU)

• Processo FAPESP: 13/50228-8 - Componentes da biodiversidade, e seus caracteres metabólicos, de ilhas do Brasil: uma abordagem integrada
• Beneficiário: Roberto Gomes de Souza Berlinck
• Modalidade de apoio: Auxílio à Pesquisa - Programa BIOTA - Temático