Feruloyl esterases: Biocatalysts to overcome biomass recalcitrance and for the production of bioactive compounds

Autor(es)

Oliveira, Dyoni M. ^[1] ; Mota, Thatiane R. ^[1] ; Oliva, Bianca ^[2] ; Segato, Fernando ^[2] ; Marchiosi, Rogerio ^[1] ; Ferrarese-Filho, Osvaldo ^[1] ; Faulds, Craig B. ^[3] ; dos Santos, Wanderley D. ^[1]

Afiliação do(s) autor(es)

^[1] Univ Estadual Maringa, Dept Biochem, Maringa, Parana - Brazil

^[2] Univ Sao Paulo, Engn Sch Lorena, Dept Biotechnol, Lorena, SP - Brazil

^[3] Aix Marseille Univ, INRA, UMR 1163, BBF, F-13009 Marseille - France

• Tipo de documento: Artigo de Revisão
• Fonte: Bioresource Technology; v. 278, p. 408-423, APR 2019.
• Citações Web of Science: 9

Resumo

Ferulic acid and its hydroxycinnamate derivatives represent one of the most abundant forms of low molecular weight phenolic compounds in plant biomass. Feruloyl esterases are part of a microorganism's plant cell wall-degrading enzymatic arsenal responsible for cleaving insoluble wall-bound hydroxycinnamates and soluble cytosolic conjugates. Stimulated by industrial requirements, accelerating scientific discoveries and knowledge transfer, continuous improvement efforts have been made to identify, create and repurposed biocatalysts dedicated to plant biomass conversion and biosynthesis of high-added value molecules. Here we review the basic knowledge and recent advances in biotechnological characteristics and the gene content encoding for feruloyl esterases. Information about several enzymes is systematically organized according to their function, biochemical properties, substrate specificity, and biotechnological applications. This review contributes to further structural, functional, and biotechnological R\&D both for obtaining hydroxycinnamates from agricultural by-products as well as for lignocellulose biomass treatments aiming for production of bioethanol and other derivatives of industrial interest. (AU)

• Processo FAPESP: 14/18714-2 - Oxidação enzimática do bagaço de cana-de-açúcar: descoberta, caracterização e aplicação de novas enzimas oxidativas de carboidratos, voltadas para o desenvolvimento de um cell factory mais eficiente
• Beneficiário: Fernando Segato
• Modalidade de apoio: Auxílio à Pesquisa - Programa BIOEN - Jovens Pesquisadores