Punicic acid was metabolised and incorporated in the form of conjugated linoleic acid in different rat tissues

Autor(es)

Pereira de Melo, Illana Louise ^[1] ; de Oliveira e Silva, Ana Mara ^[2] ; Yoshime, Luciana Tedesco ^[1] ; Gasparotto Sattler, Jose Augusto ^[1] ; Teixeira de Carvalho, Eliane Bonifacio ^[1] ; Mancini-Filho, Jorge ^[1]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Fac Pharmaceut Sci, Dept Food & Expt Nutr, Lab Lipids, Ave Prof Lineu Prestes 580, Bloco 14, BR-05508900 Sao Paulo - Brazil

^[2] Univ Fed Sergipe, Biol Sci & Hlth Ctr, Aracaju, Sergipe - Brazil

• Tipo de documento: Artigo Científico
• Fonte: INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION; v. 70, n. 4, p. 421-431, MAY 19 2019.
• Citações Web of Science: 1

Resumo

The objective of this study was to evaluate the effects of a supplementation of pomegranate seed oil (PSO), being rich in punicic acid, on the biochemical parameters of healthy rats. PSO was given to the animals intragastrically for 40 days at concentrations of 1%, 2% and 4%. There were no changes in their total body weight gain, their serum biochemical markers, or in the oxidative stress in their tissues. However, the TBARS values were reduced in the brains of the animals, noting that no significant amounts of conjugated fatty acids were found in this tissue. Conjugated linoleic acid (CLA) was present in all the other tissues studied. The results obtained have demonstrated that punicic acid from PSO was metabolised and incorporated in the form of CLA in different rat tissues. It did not cause alterations in their lipid metabolism, nor did it participate in the processes of oxidation inhibition. (AU)

• Processo FAPESP: 09/51891-7 - Avaliação em ratos do efeito dos isômeros conjugados do ácido linoleico (9cis, 11trans e 10trans, 12cis) e do ácido alfa-linolênico (9cis, 11trans, 13cis) sobre o perfil lipídico tecidual e sua influência sobre parâmetros bioquímicos em processos oxidativos
• Beneficiário: Jorge Mancini Filho
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 09/51890-0 - Avaliacao em ratos do efeito do acido graxo punicio sobre o perfil lipidico tecidual e sua influencia sobre parametros bioquimicos em processos oxidativos
• Beneficiário: Illana Louise Pereira de Melo
• Modalidade de apoio: Bolsas no Brasil - Doutorado