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Menezes, Arteiro Queiroz ^{[1, 2, 3]} ; Guerreiro Cardoso, Paulo Francisco ^[2] ; Nagao, Christopher Kengo ^[2] ; Minamoto, Helio ^[2] ; Bibas, Benoit Jacques ^[2] ; Soares Rodrigues, Isaac de Faria ^[2] ; Otoch, Jose Pinhata ^[4] ; Dolhnikoff, Marisa ^[5] ; Canzian, Mauro ^[6] ; Mancini, Marilia Wellichan ^[7] ; Pego-Fernandes, Paulo Manuel ^[2]

Afiliação do(s) autor(es)

^[1] Univ Fed Amazonas, Manaus, Amazonas - Brazil

^[2] Univ Sao Paulo, Hosp Clin, Thorac Surg Res Lab LIM 61, Div Thorac Surg, Heart Inst InCor, Fac Med, Rua Dr Eneas de Carvalho Aguiar 44, Bloco 1, BR-05403000 Sao Paulo, SP - Brazil

^[3] Univ Estado Amazonas, Dept Surg, Manaus, Amazonas - Brazil

^[4] Univ Sao Paulo, Discipline Surg Tech & Expt Surg LIM 26, Fac Med, Ave Dr Arnaldo 455, 4 Andar, BR-01246903 Sao Paulo, SP - Brazil

^[5] Univ Sao Paulo, Dept Pathol, Fac Med, Ave Dr Arnaldo 455, Sala 1155, BR-01246903 Sao Paulo, SP - Brazil

^[6] LABPAC Pathol Lab, Rua Calixto da Mota 72, BR-04117100 Sao Paulo, SP - Brazil

^[7] Nucleo Pesquisa & Ensino Fototerapia Ciencias Sau, Rua Pedro Fernandes Alonso 766, BR-13562380 Sao Carlos, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Lasers in Medical Science; v. 34, n. 7, p. 1441-1448, SEP 2019.
• Citações Web of Science: 0

Resumo

To evaluate the feasibility of a 980-nm contact diode laser (CDL) as a method for creating a posterior laryngofissure in live pigs. Twenty-eight Landrace pigs (15-20 kg) were anesthetized, intubated, ventilated, and submitted to a cervical tracheostomy. An anterior and posterior midline longitudinal laryngofissure incision was created according to randomization-control (n = 4), posterior laryngofissure with a scalpel blade; electrocautery (n = 12), posterior laryngofissure by electrocautery (10, 15, 20, 25 W powers); CDL (n = 12), posterior laryngofissure by the CDL (10, 15, 20, 25 W peak powers in pulsed mode). Larynx and proximal trachea were excised, prepared for histopathology, and digital morphometric analysis. Measurements in and within each group were analyzed (Kruskal-Wallis and Dunn test) with a level of significance of p < 0.05. Incision width was not different between the groups, as well as in the powers used in CDL (p = 0.161) and electrocautery group (p = 0.319). The depth of the incisions was smaller in the Laser group compared to control (p = 0.007), and in the electrocautery compared to control (p = 0.026). Incision area was smaller in CDL compared with the control (p = 0.027), and not different between laser and electrocautery groups (p = 0.199). The lateral thermal damage produced by electrocautery was the largest, with a significant difference between laser and electrocautery (p = 0.018), and between electrocautery and control (p = 0.004), whereas the comparison between laser and control showed no significant differences (p = 0.588). The posterior laryngofissure incision using a 980-nm CDL is feasible resulting in smaller incisional area and less lateral thermal damage. (AU)

• Processo FAPESP: 15/17847-1 - Avaliação da aplicabilidade do Laser diodo em laringes e traquéias normais de porcos.
• Beneficiário: Paulo Francisco Guerreiro Cardoso
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 16/25437-0 - Avaliação da aplicabilidade do Laser diodo em laringes e traquéias normais de porcos
• Beneficiário: Christopher Kengo Nagao
• Modalidade de apoio: Bolsas no Brasil - Iniciação Científica