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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Electrochemical degradation of the antibiotic ciprofloxacin in a flow reactor using distinct BDD anodes: Reaction kinetics, identification and toxicity of the degradation products

Texto completo
Autor(es):
Wachter, Naihara [1] ; Aquino, Jose Mario [1] ; Denadai, Marina [1] ; Barreiro, Juliana C. [2] ; Silva, Adilson Jose [3] ; Cass, Quezia B. [1] ; Bocchi, Nerilso [1] ; Rocha-Filho, Romeu C. [1]
Número total de Autores: 8
Afiliação do(s) autor(es):
[1] Univ Fed Sao Carlos, Dept Quim, CP 676, BR-13560970 Sao Carlos, SP - Brazil
[2] Univ Sao Paulo, Inst Quim Sao Carlos, Ave Joao Dagnone 1100, Ed Quim Ambiental, BR-13563120 Sao Carlos, SP - Brazil
[3] Univ Fed Sao Carlos, Dept Engn Quim, CP 676, BR-13560970 Sao Carlos, SP - Brazil
Número total de Afiliações: 3
Tipo de documento: Artigo Científico
Fonte: Chemosphere; v. 234, p. 461-470, NOV 2019.
Citações Web of Science: 0
Resumo

The performances of distinct BDD anodes (boron doping of 100, 500 and 2500 ppm, with sp(3)/sp(2) carbon ratios of 215, 325, and 284, respectively) in the electrochemical degradation of ciprofloxacin - CIP (0.5 L of 50 mg L-1 in 0.10 M Na2SO4, at 25 degrees C) were comparatively assessed using a recirculating flow system with a filter-press reactor. Performance was assessed by monitoring the CIP and total organic carbon (TOC) concentrations, oxidation intermediates, and antimicrobial activity against Escherichia coli as a function of electrolysis time. CIP removal was strongly affected by the solution pH (kept fixed), flow conditions, and current density; similar trends were obtained independently of the BDD anode used, but the BDD100 anode yielded the best results. Enhanced mass transport was achieved at a low flow rate by promoting the solution turbulence within the reactor. The fastest complete CIP removal (within 20 min) was attained at j = 30 mA cm(-2), pH = 10.0, and q(v)= 2.5 L min(-1) + bypass turbulence promotion. TOC removal was practically accomplished only after 10 h of electrolysis, with quite similar performances by the distinct BDD anodes. Five initial oxidation intermediates were identified (263 <= m/z <= 348), whereas only two terminal oxidation intermediates were detected (oxamic and formic acids). The antimicrobial activity of the electrolyzed CIP solution was almost completely removed within 10 h of electrolysis. The characteristics of the BDD anodes only had a marked effect on the CIP removal rate (best performance by the least-doped anode), contrasting with other data in the literature. (C) 2019 Elsevier Ltd. All rights reserved. (AU)

Processo FAPESP: 09/54040-8 - EMU: aquisição de um espectrômetro de massas de alta resolução Orbitrap para descoberta e elucidação estrutural compostos biologicamente ativos: aplicações em proteômica e biomarcadores, síntese, isolamento e caracterização de produtos naturais, estudos de sistemas redox em alimentos e síntese enzimática
Beneficiário:Emanuel Carrilho
Linha de fomento: Auxílio à Pesquisa - Programa Equipamentos Multiusuários
Processo FAPESP: 09/17138-0 - Métodos para análises de pequenas moléculas em fluidos biológicos: o uso de colunas de meios de acesso restrito para injeção direta de amostras
Beneficiário:Quezia Bezerra Cass
Linha de fomento: Auxílio à Pesquisa - Regular
Processo FAPESP: 12/13002-9 - Degradação eletroquímica de um fármaco: comparação entre ânodos
Beneficiário:Naihara Wachter
Linha de fomento: Bolsas no Brasil - Mestrado