Effects of an Er,Cr:YSGG Laser on Bone Regeneration in Critical-Sized Calvarial Defects of Rats Exposed to Inhalation of Cigarette Smoke

Autor(es)

Pavone, Chaine ^[1] ; Scardueli, Cassio Rocha ^[2] ; Pimentel Lopes de Oliveira, Guilherme Jose ^[3] ; Cerri, Paulo Sergio ^[4] ; Marcantonio Junior, Elcio ^[2] ; Chierici Marcantonio, Rosemary Adriana ^[2]

Afiliação do(s) autor(es)

^[1] Unicastelo, Sch Dent, Descalvado - Brazil

^[2] Sao Paulo State Univ Unesp, Dept Diag & Surg, Sch Dent Araraquara, Humaita St 1680, BR-14801130 Araraquara - Brazil

^[3] Univ Fed Uberlandia, Dept Periodontol, Uberlandia, MG - Brazil

^[4] Sao Paulo State Univ Unesp, Dept Pathol & Physiol, Sch Dent Araraquara, Araraquara - Brazil

• Tipo de documento: Artigo Científico
• Fonte: PHOTOBIOMODULATION PHOTOMEDICINE AND LASER SURGERY; v. 37, n. 8, p. 500-507, AUG 2019.
• Citações Web of Science: 0

Resumo

Objective: To evaluate the effect of the Er,Cr:YSGG laser on healing of critical-sized calvarial defects (CSDs) in rats submitted to inhalation of cigarette smoke. Background: Smoking has been implicated with the delay in the bone healing after osteotomy procedures, then the use of the Er,Cr:YSGG laser for osteotomy in smokers could be an alternative to the conventional drills. Methods: One hundred animals were randomly allocated into four groups: trephine-the CSDs were made with a trephine drill in healthy rats; Er,Cr:YSGG-the CSDs were made with the Er,Cr:YSGG laser in healthy rats; Trephine-S-the CSDs were made with a trephine drill in rats exposed to cigarette smoke; and Er,Cr:YSGG-S-the CSDs were made with the Er,Cr:YSGG laser in rats exposed to cigarette smoke. The inhalation of cigarette smoke started 7 days before the surgical procedure until euthanasia (immediately, 7, 15, 30, or 60 days after the surgical procedure). A histometric analysis and a histological description were performed to evaluate (1) the residual linear lengths and bone formation in the CSDs; (2) the quality of bone healing. Results: The use of Er,Cr:YSGG laser induces more bone formation compared with the trephine in smokers; however, the closure of the CSD was only superior in the Er,Cr:YSGG-S group compared to the Trephine-S group at the 60-day period. Conclusions: The use of the Er,Cr:YSGG laser stimulated the bone repair process after osteotomy procedures in animals submitted to exposure of inhalation of cigarette smoke. (AU)

• Processo FAPESP: 10/16661-8 - Avaliação dos efeitos do laser Er,Cr:YSGG em defeitos ósseos críticos e no tratamento de doença periodontal induzida em ratos submetidos a inalação de fumaça de cigarro
• Beneficiário: Rosemary Adriana Chierici Marcantonio
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 09/17639-9 - Avaliação dos efeitos do Laser ER,CR:YSGG em defeitos ósseos críticos e no tratamento de doença periodontal induzida em ratos submetidos a inalação de fumaça de cigarro.
• Beneficiário: Chaine Pavone
• Modalidade de apoio: Bolsas no Brasil - Doutorado