Remineralization of early enamel caries lesions induced by bioactive particles: An in vitro speckle analysis

Autor(es)

Sfalcin, Ravana Angelini ^[1] ; Pereira da Silva, Joao Vagner ^[1] ; Pessoa, Victoria Oliva ^[2] ; Santos, Jennifer ^[2] ; Garcia Olivan, Silvia Regina ^[1] ; Santos Fernandes, Kristianne Porta ^[1] ; Deana, Alessandro Melo ^[1] ; Makeeva, Irina ^[3] ; Sauro, Salvatore ^{[3, 4]} ; Bussadori, Sandra Kalil ^{[1, 5]}

Afiliação do(s) autor(es)

^[1] Univ Nove Julho UNINOVE, Postgrad Program Biophoton Appl Hlth Sci & Rehabi, Rua Vergueiro 235-249, BR-01504001 Liberdade, SP - Brazil

^[2] Univ Nove Julho UNINOVE, Program Biophoton Appl Hlth Sci & Rehabil Sci, Rua Vergueiro 235-249, BR-01504001 Liberdade, SP - Brazil

^[3] Sechenov Univ, Dept Therapeut Dent, Mozhaisky Val 11, Moscow 119435 - Russia

^[4] Univ CEU, Biomat Prevent & Minimally Invas Dent, Dept Odontol, Fac Ciencias Salud, C Pozo S-N, Valencia - Spain

^[5] Rua Vergueiro 235-249, BR-01504001 Liberdade, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Photodiagnosis and Photodynamic Therapy; v. 28, p. 201-209, DEC 2019.
• Citações Web of Science: 0

Resumo

This study aimed at evaluating the remineralization effect promoted by different bioactive fillers on simulated early caries lesions in enamel (ECLE). Forty sound bovine incisors were used to prepare buccal enamel specimens (6 x 6 x 2 mm). The specimens were divided into two areas (3 x 3 mm(2)): control (CTR) and experimental (EXP). All the enamel specimens were then submitted to a specific protocol for a period of 48 h to induce simulated caries lesions. Subsequently, the specimens were treated for 7 days (2 min, twice a day) with a slurry pastes containing different bioactive particles (P/L ratio: 1 g/mL). All the specimens were analyzed by laser speckle before and after treatments. The results showed after the first analysis that the ECLE had very low average intensity (back-scattered light). Conversely, after application of the bioactive pastes, higher average intensity was always detected; this was comparable to CTR sound specimens. In conclusion, innovative pastes/gels developed for enamel remineralization should contain bioactive particles that when applied daily on early caries lesions may ``boost{''} the remineralization process to reestablish a sound enamel. (AU)

• Processo FAPESP: 15/25180-7 - Visão computacional aliada a iluminação coerente aplicada a processos de diagnóstico em odontologia
• Beneficiário: Alessandro Melo de Ana
• Modalidade de apoio: Auxílio à Pesquisa - Regular