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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Remineralization of early enamel caries lesions induced by bioactive particles: An in vitro speckle analysis

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Author(s):
Sfalcin, Ravana Angelini [1] ; Pereira da Silva, Joao Vagner [1] ; Pessoa, Victoria Oliva [2] ; Santos, Jennifer [2] ; Garcia Olivan, Silvia Regina [1] ; Santos Fernandes, Kristianne Porta [1] ; Deana, Alessandro Melo [1] ; Makeeva, Irina [3] ; Sauro, Salvatore [3, 4] ; Bussadori, Sandra Kalil [1, 5]
Total Authors: 10
Affiliation:
[1] Univ Nove Julho UNINOVE, Postgrad Program Biophoton Appl Hlth Sci & Rehabi, Rua Vergueiro 235-249, BR-01504001 Liberdade, SP - Brazil
[2] Univ Nove Julho UNINOVE, Program Biophoton Appl Hlth Sci & Rehabil Sci, Rua Vergueiro 235-249, BR-01504001 Liberdade, SP - Brazil
[3] Sechenov Univ, Dept Therapeut Dent, Mozhaisky Val 11, Moscow 119435 - Russia
[4] Univ CEU, Biomat Prevent & Minimally Invas Dent, Dept Odontol, Fac Ciencias Salud, C Pozo S-N, Valencia - Spain
[5] Rua Vergueiro 235-249, BR-01504001 Liberdade, SP - Brazil
Total Affiliations: 5
Document type: Journal article
Source: Photodiagnosis and Photodynamic Therapy; v. 28, p. 201-209, DEC 2019.
Web of Science Citations: 0
Abstract

This study aimed at evaluating the remineralization effect promoted by different bioactive fillers on simulated early caries lesions in enamel (ECLE). Forty sound bovine incisors were used to prepare buccal enamel specimens (6 x 6 x 2 mm). The specimens were divided into two areas (3 x 3 mm(2)): control (CTR) and experimental (EXP). All the enamel specimens were then submitted to a specific protocol for a period of 48 h to induce simulated caries lesions. Subsequently, the specimens were treated for 7 days (2 min, twice a day) with a slurry pastes containing different bioactive particles (P/L ratio: 1 g/mL). All the specimens were analyzed by laser speckle before and after treatments. The results showed after the first analysis that the ECLE had very low average intensity (back-scattered light). Conversely, after application of the bioactive pastes, higher average intensity was always detected; this was comparable to CTR sound specimens. In conclusion, innovative pastes/gels developed for enamel remineralization should contain bioactive particles that when applied daily on early caries lesions may ``boost{''} the remineralization process to reestablish a sound enamel. (AU)

FAPESP's process: 15/25180-7 - Computer vision coupled with coherent illumination applied to diagnostic procedures in odontology
Grantee:Alessandro Melo de Ana
Support Opportunities: Regular Research Grants