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Texto completo
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| Autor(es): |
dos Santos Silva, Danielly Beraldo
[1, 2]
;
Simielli Fonseca, Larissa Fernanda
[1, 2]
;
Braga Magalhaes, Ana Fabricia
[3]
;
Magalhaes Muniz, Maria Malane
[2]
;
Baldi, Fernando
[1, 2]
;
Ferro, Jesus Aparecido
[1, 2]
;
Loyola Chardulo, Luis Artur
[4]
;
Pinheiro, Daniel Guariz
[2]
;
de Albuquerque, Lucia Galvao
[1, 2]
Número total de Autores: 9
|
| Afiliação do(s) autor(es): | [1] Natl Council Sci & Technol Dev CNPq, Brasilia, DF - Brazil
[2] Sao Paulo State Univ, UNESP, Sch Agr & Vet Sci, Jaboticabal, SP - Brazil
[3] Adv Res Ctr Beef Cattle, IZ, Sertaozinho, SP - Brazil
[4] Sao Paulo State Univ, UNESP, Sch Vet & Anim Sci, Botucatu, SP - Brazil
Número total de Afiliações: 4
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| Tipo de documento: |
Artigo Científico
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| Fonte: |
Genomics;
v. 112,
n. 2,
p. 1257-1263,
MAR 2020.
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| Citações Web of Science: |
0
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| Resumo |
This study aimed to use RNA-Seq to identify differentially expressed genes (DEGs) in muscle of uncastrated Nelore males phenotypically divergent for ribeye muscle area (REA). A total of 80 animals were phenotyped for REA, and 15 animals each with the highest REA and the lowest REA were selected for analyses. DEGs found (N = 288) belonging to families related to muscle cell growth, development, motility and proteolysis, such as actin, myosin, collagen, integrin, solute carrier, ubiquitin and kelch-like. Functional analysis showed that many of the significantly enriched gene ontology terms were closely associated with muscle development, growth, and degradation. Through co-expression network analysis, we predicted three hub genes (PPP3R1, FAM129B and UBE2G1), these genes are involved in muscle growth, proteolysis and immune system. The genes expression levels and its biological process found this study may result in differences in muscle deposition, and therefore, Nelore animals with different REA proportions. (AU) |
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| Processo FAPESP: |
09/16118-5 - Ferramentas genômicas no melhoramento genético de características de importância econômica direta em bovinos da raça Nelore
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| Beneficiário: | Lucia Galvão de Albuquerque |
| Linha de fomento: |
Auxílio à Pesquisa - Temático
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| Processo FAPESP: |
15/16850-9 - Expressão diferencial de genes relacionados com caraterísticas da carcaça e carne de bovinos da raça Nelore
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| Beneficiário: | Danielly Beraldo dos Santos Silva |
| Linha de fomento: |
Bolsas no Brasil - Doutorado
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