Bleaching gel mixed with MI Paste Plus reduces penetration of H2O2 and damage to pulp tissue and maintains bleaching effectiveness

Autor(es)

Barbosa, Jessica Galbiati ^[1] ; Benetti, Francine ^{[1, 2]} ; De Oliveira Gallinari, Marjorie ^[3] ; Carminatti, Marina ^[1] ; Da Silva, Anna Beatriz Dias ^[1] ; Lopes, Isabela Nakahara Ikeda ^[1] ; Briso, Andre Luiz Fraga ^[3] ; Cintra, Luciano Tavares Angelo ^[1]

Afiliação do(s) autor(es)

^[1] Sao Paulo State Univ, Sch Dent, Dept Endodont, Unesp, Aracatuba, SP - Brazil

^[2] Universidade Fed Minas Gerais, Sch Dent, Restorat Dent, UFMG, Belo Horizonte, MG - Brazil

^[3] Sao Paulo State Univ, Sch Dent, Dept Restorat Dent, Unesp, Aracatuba, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: CLINICAL ORAL INVESTIGATIONS; v. 24, n. 3, p. 1299-1309, MAR 2020.
• Citações Web of Science: 1

Resumo

Objectives MI Paste Plus remineralizer (Rem) strengthens dental structures after bleaching. We investigated the effect of Rem on the penetration of hydrogen peroxide (H2O2), bleaching effectiveness, and pulp inflammation after bleaching. Materials and methods Bovine disks were grouped as follows (n = 10): control (untreated), bleached (Ble; 35% H2O2, 30 min), Ble-Rem (H2O2 followed by Rem, 30 min), Rem-Ble (Rem followed by H2O2), Rem-Ble-Rem (Rem before and after H2O2), and Ble+Rem (mixture of Rem with H2O2, 1:1, 30 min). The penetration of H2O2 was quantified and bleaching efficacy was analyzed. Upper rat molars (n = 10) received the same treatments at random. The rats were euthanized after two days and 30 days, and their jaws were removed for histological analysis. Statistical tests were performed (P < 0.05). Results The bleached groups, except Ble+Rem (P > 0.05), showed significant H2O2 penetration compared with control (P < 0.05). Color alteration analysis showed that Delta L and Delta E were significantly higher in the bleached groups than those in control (P < 0.05); the Delta b of the bleached groups differed from that of control at 24 h (P < 0.05). At two days, necrosis or inflammation was observed in the bleached groups compared with control (P < 0.05), except Ble+Rem, which was similar to control (P > 0.05). At 30 days, tertiary dentin formation was significant in the bleached groups (P < 0.05), except Ble+Rem (P > 0.05). Conclusion The mixture of MI Paste Plus and bleaching gel reduces H2O2 penetration and pulp damage and maintains bleaching effectiveness. (AU)

• Processo FAPESP: 15/10984-3 - Avaliação do tecido pulpar de molares de ratos Wistar submetidos a procedimento clareador e diferentes protocolos de aplicação do remineralizante MI Paste Plus: um estudo in vivo
• Beneficiário: Jéssica Galbiati Barbosa
• Modalidade de apoio: Bolsas no Brasil - Iniciação Científica