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Metabolization of Insecticidal Amides from Leaves of Piper tuberculatum by Heraclydes hectorides and Naupactus bipes

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Autor(es):
Ramos, Clecio S. [1] ; Silva, Marcilio W. F. [1] ; Moraes, Marcilio M. [2] ; Almeida, V, Argus ; Vanin, Sergio A. [3] ; Kato, Massuo J. [2]
Número total de Autores: 6
Afiliação do(s) autor(es):
[1] Univ Fed Rural Pernambuco, Dept Quim, BR-52171030 Recife, PE - Brazil
[2] Univ Sao Paulo, Dept Quim Fundamental, Inst Quim, BR-05508000 Sao Paulo, SP - Brazil
[3] Univ Sao Paulo, Inst Biociencias, BR-05513970 Sao Paulo, SP - Brazil
Número total de Afiliações: 3
Tipo de documento: Artigo Científico
Fonte: Journal of the Brazilian Chemical Society; v. 31, n. 4, p. 724-730, APR 2020.
Citações Web of Science: 0
Resumo

Amides have been recognized as potent insecticidal natural products but, despite their variety of targets and mechanisms of action, their metabolic fate in insects is virtually unknown. The currently accepted hypothesis is that specialist herbivores are capable of biotransforming xenobiotics rendering them more polar and excretable while generalist insects do not have comparable capacity. The leaves from Piper tuberculatum, rich in insecticide amides, were offered to two insect species found on Piper leaves under natural conditions and also to four generalist grasshoppers in order to compare their capacity of biotransforming xenobiotics. The amides 1-7 were identified in the P. tuberculatum leaves and their corresponding carboxylic acids 8-13 were detected in frass samples of two host insects suggesting that these species promote the amides hydrolysis. The four generalist grasshoppers when offered P. tuberculatum leaves, starved to death after 72 h, indicating a strong antifeedant activity of P. tuberculatum leaves. (AU)

Processo FAPESP: 09/51850-9 - Diversidade molecular em Angiospermas basais
Beneficiário:Massuo Jorge Kato
Modalidade de apoio: Auxílio à Pesquisa - Programa BIOEN - Temático
Processo FAPESP: 14/50316-7 - Dimensões US-BIOTA São Paulo: diversidade de interações multi-tróficas quimicamente mediadas em gradientes nos trópicos
Beneficiário:Massuo Jorge Kato
Modalidade de apoio: Auxílio à Pesquisa - Programa BIOTA - Temático