Unvealing the role of beta-Ag2MoO4 microcrystals to the improvement of antibacterial activity

Autor(es)

De Foggi, Camila Cristina ^[1] ; De Oliveira, Regiane Cristina ^[2] ; Assis, Marcelo ^[2] ; Fabbro, Maria Tereza ^[2] ; Mastelaro, Valmor Roberto ^[3] ; Vergani, Carlos Eduardo ^[1] ; Gracia, Lourdes ^[4] ; Andres, Juan ^[4] ; Longo, Elson ^[2] ; Machado, Ana Lucia ^[1]

Afiliação do(s) autor(es)

^[1] Sao Paulo State Univ, Dept Dent Mat & Prosthodont, UNESP, BR-14801907 Sao Paulo - Brazil

^[2] Univ Fed Sao Carlos, Interdisciplinary Lab Electrochem & Ceram, POB 676, BR-13565905 Sao Carlos, SP - Brazil

^[3] Univ Sao Paulo, Sao Carlos Inst Phys, CP 369, BR-13560970 Sao Carlos, SP - Brazil

^[4] Univ Jaume 1, Dept Phys & Analyt Chem, Campus Riu Sec, E-12071 Castellon de La Plana - Spain

• Tipo de documento: Artigo Científico
• Fonte: Materials Science & Engineering C-Materials for Biological Applications; v. 111, JUN 2020.
• Citações Web of Science: 0

Resumo

Crystal morphology with different surfaces is important for improving the antibacterial activity of materials. In this experimental and theoretical study, the antibacterial activity of beta-Ag2MoO4 microcrystals against the Gram-positive bacteria, namely, methicillin-resistant Staphylococcus aureus (MRSA), and the Gram-negative bacteria, namely, Escherichia coli (E. coli), was investigated. In this study, beta-Ag2MoO4 crystals with different morphologies were synthesized by a simple co-precipitation method using three different solvents. The antimicrobial efficacy of the obtained microcrystals against both bacteria increased according to the solvent used in the following order: water < ammonia < ethanol. Supported by experimental evidence, a correlation between morphology, surface energy, and antibacterial performance was established. By using the theoretical Wulff construction, which was obtained by means of density functional calculations, the morphologies with large exposition of the (001) surface exhibited superior antibacterial activity. This study provides a low cost route for synthesizing beta-Ag2MoO4 crystals and a guideline for enhancing the biological effect of biocides on pathogenic bacteria by the morphological modulation. (AU)

• Processo FAPESP: 13/07296-2 - CDMF - Centro de Desenvolvimento de Materiais Funcionais
• Beneficiário: Elson Longo da Silva
• Modalidade de apoio: Auxílio à Pesquisa - Centros de Pesquisa, Inovação e Difusão - CEPIDs
• Processo FAPESP: 15/03654-7 - Ação antimicrobiana de óxidos bimetálicos e de revestimento depositado a plasma sobre resina acrílica
• Beneficiário: Camila Cristina de Foggi
• Modalidade de apoio: Bolsas no Brasil - Doutorado Direto