| Texto completo | |
| Autor(es): |
Número total de Autores: 2
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| Afiliação do(s) autor(es): | [1] Univ Sao Paulo, Fac Ciencias Farmaceut, Dept Farm, Ave Prof Lineu Prestes 580, BR-05508000 Sao Paulo - Brazil
[2] Stefani, Helio A., Univ Sao Paulo, Fac Ciencias Farmaceut, Dept Farm, Ave Prof Lineu Prestes 580, BR-05508000 Sao Paulo, Brazil.Soares-Paulino, Antonio Augusto, Univ Sao Paulo, Fac Ciencias Farmaceut, Dept Farm, Ave Prof Lineu Prestes 580, BR-05508000 Sao Paulo - Brazil
Número total de Afiliações: 2
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| Tipo de documento: | Artigo Científico |
| Fonte: | EUROPEAN JOURNAL OF ORGANIC CHEMISTRY; v. 2020, n. 25 JUN 2020. |
| Citações Web of Science: | 0 |
| Resumo | |
Herein, we describe the synthesis of acyl azides and acyl urea glycals, a new class of C-2 branched glycoconjugates, employing Pd-catalyzed carbonylative coupling. A new strategy was developed to obtain acyl azides by carbonylative coupling between 2-iodo-glycals and NaN(3)catalyzed by Pd(dba)(2)/Xantphos and carbon monoxide as a carbonyl source. Acyl azide glycals were used as synthetic intermediates in obtaining new acyl urea glycals via carbonylative coupling catalyzed by Pd(OAc)(2)and 1,10-Phen. Different glycal substrates, including disaccharide-type, were studied, and various acyl azides and acyl ureas were prepared. Reaction yields were moderate to high (31-99 %) and reaction time varying from short to long (0.5-20 h). (AU) | |
| Processo FAPESP: | 14/50316-7 - Dimensões US-BIOTA São Paulo: diversidade de interações multi-tróficas quimicamente mediadas em gradientes nos trópicos |
| Beneficiário: | Massuo Jorge Kato |
| Modalidade de apoio: | Auxílio à Pesquisa - Programa BIOTA - Temático |
| Processo FAPESP: | 18/10108-7 - Reações de Cicloadição Intermolecular [2+2] Emnpregando D-Glucal |
| Beneficiário: | Antonio Augusto Soares Paulino |
| Modalidade de apoio: | Bolsas no Brasil - Pós-Doutorado |
| Processo FAPESP: | 17/24821-4 - Reações de Acoplamento Carbonilativo e Cicloadição [2+2] Intramolecular Empregando D-Glucal |
| Beneficiário: | Helio Alexandre Stefani |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |