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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Connaraceae: An updated overview of research and the pharmacological potential of 39 species

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Autor(es):
Nunes Alves Paim, Luis Fernando [1] ; Patrocinio Toledo, Cassio Augusto [2] ; Lima da Paz, Joicelene Regina [3] ; Picolotto, Aline [1] ; Ballardin, Guilherme [1] ; Souza, Vinicius Castro [2] ; Salvador, Mirian [4] ; Moura, Sidnei [1]
Número total de Autores: 8
Afiliação do(s) autor(es):
[1] Univ Caxias do Sul, Lab Biotechnol Nat & Synthet Prod, Caxias Do Sul, RS - Brazil
[2] Univ Estadual Campinas, UNICAMP, Programa Posgrad Biol Vegetal, Campinas - Brazil
[3] Univ Brasilia, Programa Posgrad Bot, Brasilia, DF - Brazil
[4] Univ Caxias do Sul, Biotechnol Inst, Lab Oxidat Stress & Antioxidants, Caxias Do Sul, RS - Brazil
Número total de Afiliações: 4
Tipo de documento: Artigo Científico
Fonte: Journal of Ethnopharmacology; v. 261, OCT 28 2020.
Citações Web of Science: 0
Resumo

Ethnopharmacological relevance: An interdisciplinary scientific investigation of biologically active agents is fundamental to search for natural substances with therapeutic action. This review collected the most relevant information on traditional knowledge related to the use of plants of the Connaraceae family. This work is the first to compile all the published ethnobotanical, chemical, pharmacological, and toxicological information about this important plant family. Aim of the study: Our objective was to provide the scientific community with an up-to-date overview of the pharmacological potential of Connaraceae species. Material and methods: We searched NCBI Pubmed Central, Google Scholar, Scientific Electronic Library Online (SciELO), ScienceDirect, SciFinder, and Scopus databases to review the research on ethnobotanical, chemical, pharmacognostical, pharmacological, and toxicological studies with Connaraceaes. Books that address the theme were also included. Discussion and conclusion: The literature review indicated that 39 species of Connaraceaes have pharmacological potentiality. Ethnobotany reports listed 36 of the 39 species discussed. Pharmacognostical studies have been conducted with 23 species and isolates, and chemical compounds have been identified for only 15 species. At least one study has been published concerning the pharmacological activities for 20 of the 39 species analyzed. For Agelaea pentagyna, Cnestis ferruginea, Connars suberosus, and Rourea minor, pharmacological activity experiments were performed using isolated compounds, which have the highest current pharmacological potential. Studies employing a toxicological approach cover only 10 of the 39 Connaraceaes species. Thus, scientific community should conduct much more research for a broader understanding of this plant family. (AU)

Processo FAPESP: 19/03173-0 - Estudos sistemáticos, ontogenéticos, reprodutivos e fitoquímicos em Connaraceae, com ênfase nas espécies neotropicais
Beneficiário:Vinicius Castro Souza
Modalidade de apoio: Auxílio à Pesquisa - Regular