| Texto completo | |
| Autor(es): |
Ballard, Cintia Reis
[1]
;
dos Santos, Elisvania Freitas
[2]
;
Dubois, Marie-Julie
[3]
;
Pilon, Genevieve
[3]
;
Betim Cazarin, Cinthia Bau
[1]
;
Marostica Junior, Mario Roberto
[1]
;
Marette, Andre
[3]
Número total de Autores: 7
|
| Afiliação do(s) autor(es): | [1] Univ Estadual Campinas, Sch Food Engn, Dept Food & Nutr, 80 Monteiro Lobato, BR-13083862 Campinas, SP - Brazil
[2] Univ Fed Mato Grosso do Sul, Sch Pharmaceut Sci Food & Nutr, S-N Costa & Silva, BR-79070900 Campo Grande, MS - Brazil
[3] Laval Univ, Laval Hosp, Quebec Heart & Lung Inst, 2725 St Foy, Quebec City, PQ G1V 4G5 - Canada
Número total de Afiliações: 3
|
| Tipo de documento: | Artigo Científico |
| Fonte: | FOOD & FUNCTION; v. 11, n. 10, p. 8800-8810, OCT 1 2020. |
| Citações Web of Science: | 0 |
| Resumo | |
Consumption of polyphenol-rich food is associated with better metabolic health. Tucum-do-Pantanal (Bactris setosa Mart) and taruma-do-cerrado (Vitex cymosa Bertero ex Spreng) are underexploited native Brazilian fruits with an important source of phytochemicals. In this study, we assessed the effects of 100 mg kg(-1)tucum (TPE) and taruma (TCE) extracts on diet-induced obesity (DIO) C57BL/6J mice. After 8 weeks of daily treatment, TPE and TCE were found to significantly prevented the diet-induced body weight gain and fully protected against hepatic steatosis associated with a tendency to stimulate hepatic AMPK phosphorylation. TPE reduced visceral obesity and improved glucose metabolism as revealed by an improvement of the insulin tolerance test, a reduction in the insulin fasting level, and a decreased glucose-induced hyperinsulinemia during an oral glucose tolerance test. TPE and TCE showed promising effects on the treatment of obesity and NAFLD, furthermore, TPE on insulin resistance. (AU) | |
| Processo FAPESP: | 15/50333-1 - Cobra: nova plataforma de descoberta de compostos para identificação rápida e de baixo custo de bioativo com efeitos benéficos originários de plantas brasileiras |
| Beneficiário: | Glaucia Maria Pastore |
| Modalidade de apoio: | Auxílio à Pesquisa - Temático |