Application of Dispersive Liquid-Liquid Microextraction Followed by High-Performance Liquid Chromatography/Tandem Mass Spectrometry Analysis to Determine Tetrabromobisphenol A in Complex Matrices

Autor(es)

Macedo, Williane Vieira ^[1] ; Bernegossi, Aline Christine ^[2] ; Sabatini, Carolina Aparecida ^[1] ; Corbi, Juliano Jose ^[2] ; Zaiat, Marcelo ^[1]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Sao Carlos Sch Engn, Biol Proc Lab, Sao Carlos, SP - Brazil

^[2] Univ Sao Paulo, Sch Engn Sao Carlos, Dept Hydraul Engn & Sanitat, Aquat Ecol Lab, Sao Carlos, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Environmental Toxicology and Chemistry; v. 39, n. 11, p. 2147-2157, NOV 2020.
• Citações Web of Science: 0

Resumo

An accurate and sensitive ultrasound-dispersive liquid-liquid microextraction technique followed by high-performance liquid chromatography separation coupled with electrospray ionization tandem mass spectrometry detection method to determine the presence of tetrabromobisphenol A (TBBPA) in complex environmental matrices is proposed. The miniaturized procedure was used to extract and quantify the analyte in domestic sewage, anaerobic sludge, and the aquatic test organism speciesDaphnia magnaandChironomus sancticaroli, which are standardized organisms for ecotoxicity bioassays. Limits of detection of 2 ng L-1(domestic sewage), 2 ng g(-1)(anaerobic sludge), 0.25 ng g(-1)(D. magna), and 5 ng g(-1)(C. tentans) were obtained. The presence of TBBPA was determined in domestic sewage and anaerobic sludge from an anaerobic batch bioreactor at a concentration of 0.2 +/- 0.03 mu g L(-1)and 507 +/- 79 ng g(-1), respectively. InD. magnaandC. sancticaroliexposed to TBBPA in an acute toxicity bioassay, the micropollutant accumulated at 3.74 and 8.87 mu g g(-1), respectively. The proposed method is a simple and cost-effective tool to determine TBBPA environmental occurrence and biomagnification potential compared with conventional extraction methods. To the best of our knowledge, this is the first liquid-liquid miniaturized extraction method to be applied toD. magnaandC. sancticaroli. Environ Toxicol Chem2020;00:1-11. (c) 2020 SETAC (AU)

• Processo FAPESP: 18/17744-6 - Sistema combinado para a degradação do Tetrabromobisfenol a (TBBPA) por digestão anaeróbia e processos oxidativos avançados
• Beneficiário: Williane Vieira Macêdo
• Modalidade de apoio: Bolsas no Brasil - Doutorado
• Processo FAPESP: 15/06246-7 - Aplicação do conceito de biorrefinaria a estações de tratamento biológico de águas residuárias: o controle da poluição ambiental aliado à recuperação de matéria e energia
• Beneficiário: Marcelo Zaiat
• Modalidade de apoio: Auxílio à Pesquisa - Temático