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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Residential traffic exposure and lymphohematopoietic malignancies among children in the city of Sao Paulo, Brazil: An ecological study

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Autor(es):
Ribeiro, Adeylson Guimaraes [1] ; Vermeulen, Roel [2] ; Alves Cardoso, Maria Regina [3] ; Dias de Oliveira Latorre, Maria do Rosario [3] ; Hystad, Perry [4] ; Downward, George Stanley [2] ; Nardocci, Adelaide Cassia [5]
Número total de Autores: 7
Afiliação do(s) autor(es):
[1] Barretos Canc Hosp, Educ & Res Inst, R Antenor Duarte Villela 1331, BR-14784400 Barretos, SP - Brazil
[2] Univ Utrecht, Inst Risk Assessment Sci, POB 80178, NL-3508 TD Utrecht - Netherlands
[3] Univ Sao Paulo, Sch Publ Hlth, Dept Epidemiol, Av Dr Arnaldo 715, BR-01246904 Sao Paulo, SP - Brazil
[4] Oregon State Univ, Coll Publ Hlth & Human Sci, 20C Milam Hall, Corvallis, OR 97331 - USA
[5] Univ Sao Paulo, Sch Publ Hlth, Dept Environm Hlth, Av Dr Arnaldo 715, BR-01246904 Sao Paulo, SP - Brazil
Número total de Afiliações: 5
Tipo de documento: Artigo Científico
Fonte: CANCER EPIDEMIOLOGY; v. 70, FEB 2021.
Citações Web of Science: 0
Resumo

Background: Despite widespread evidence that air pollution is carcinogenic, there is little evidence from lowmiddle income countries, especially related to childhood malignancies. We examined the role of traffic related pollution on lymphohematopoietic malignancies among under-14 s in Sao Paulo. Methods: All incident cases between 2002 and 2011 were collected from a population-based registry. Exposures were assigned on residential address at diagnosis via traffic density database (for the year 2008) and a satellite derived NO2 land use regression model (averaged between 1997 and 2011). Incidence rate ratios (IRRs) were calculated via Poisson Regression adjusted by age, gender and socioeconomic status (SES), with additional stratification by SES. Results: A positive association between traffic and NO2 with some lymphohematopoietic malignancies was observed with the degree of effect differing by SES. For example, lymphoid leukemia IRRs in the lower SES group were 1.21 (95 % CI: 1.06, 1.39) for traffic density and 1.38 (95 % CI: 1.13, 1.68) for NO2. In the higher group they were 1.06 (95 % CI: 1.00, 1.14) and 1.37 (95 % CI: 1.16, 1.62). Conclusion: NO2 and traffic density were associated with Hodgkin lymphoma and lymphoid leukemia among children in Sao Paulo. Differing IRRs by gender and SES group indicate differences in underlying risk and/or exposure profiles. (AU)

Processo FAPESP: 06/61616-5 - Estudo da relação entre doenças respiratórias e cardiovasculares e poluição veicular nas regiões metropolitanas do estado de São Paulo com a finalidade de subsidiar a estruturação das atividades do programa de vigilância em saúde e qualidade do ar
Beneficiário:Maria Regina Alves Cardoso
Modalidade de apoio: Auxílio à Pesquisa - Pesquisa em Políticas Públicas para o SUS